{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:04:08Z","timestamp":1790949848839,"version":"4.1.0"},"reference-count":66,"publisher":"IMR Press","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Vitamin and Nutrition Research"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p> Abstract. Background: Vitamin D deficiency (VDD) is a major public health problem. There are few comprehensive systematic reviews about the relationship between Vitamin D status and liver and renal disease in Iran. <\/jats:p><jats:p> Methods: We systemically searched the following databases: Web of Science; PubMed; Cochrane Library; Scopus; Science Direct; Google Scholar and two Iranian databases (Scientific Information Database (SID) and IranMedex) up until November 2017 to identify all randomized control trials\u00a0(RCTs), case control, cross-sectional and cohort studies investigating the association between vitamin D and any form of liver or kidney disease. <\/jats:p><jats:p> Results: Vitamin D insufficiency, or deficiency (VDD), is highly prevalent in Iran, reports varying between 44.4% in Isfahan to 98% in Gorgan. There is also a high prevalence of VDD among patients with liver or kidney disease, and the administration of vitamin D supplements may have beneficial effects on lipid profile, blood glucose, liver function and fatty liver disease, and bone health. Low serum vitamin D levels are related with abnormalities in these laboratory and clinical parameters. <\/jats:p><jats:p> Conclusion: VDD is prevalent in patients with chronic liver or renal disease in Iran. There appear to be several beneficial effects of vitamin D supplementation in vitamin D deficient patients with liver or kidney disease. <\/jats:p>","DOI":"10.1024\/0300-9831\/a000540","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T16:00:34Z","timestamp":1551369634000},"page":"175-187","source":"Crossref","is-referenced-by-count":12,"title":["Association of vitamin D status with liver and kidney disease: A systematic review of clinical trials, and cross-sectional and cohort studies"],"prefix":"10.31083","volume":"91","author":[{"given":"Seyed Mostafa","family":"Parizadeh","sequence":"first","affiliation":[{"name":"Metabolic Syndrome Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid","family":"Rezayi","sequence":"additional","affiliation":[{"name":"Metabolic Syndrome Research Center, School of Medicine, Mashhad University of Medical 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