{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T21:58:55Z","timestamp":1774043935105,"version":"3.50.1"},"reference-count":18,"publisher":"IMR Press","issue":"3-4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Vitamin and Nutrition Research"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p> Abstract. The world is currently overwhelmed by a novel coronavirus disease (COVID-19). Clinically, COVID-19 shows a broad range of manifestations: from asymptomatic to severe and possibly lethal interstitial pneumonia. Several studies suggested the involvement of Vitamin-D (VitD) in reducing the risk of COVID-19 infections\/severity. However, most of them are based on circumstantial evidences, like the association between latitude-related sunlight exposure and mortality rate, while studies based on patients\u2019 VitD measurements are still scarce. Therefore, we retrospectively analyzed the VitD levels (measured as 25-hydroxyvitamin-D) from a cohort of 347 patients admitted to a northern Italian Hospital as suspected COVID-19s. Of them, 128 were positive (83 males, aged 62.7\u00a0\u00b1\u00a014.2 and 45 females, aged 69.3\u00a0\u00b1\u00a015.6) and 219 were negative (107 males, aged 62.8\u00a0\u00b1\u00a019.5 and 112 females, aged 54.3\u00a0\u00b1\u00a020.1). The averaged VitD levels were similar in the two groups: 21.8\u00a0\u00b1\u00a016.1\u00a0ng\/mL and 22.8\u00a0\u00b1\u00a014.0\u00a0ng\/mL for the COVID-19 positive and negative group respectively ( p-value: 0.39), as well as the percentage of individuals having VitD levels below 30\u00a0ng\/mL: 78.9% and 73.5% for the COVID-19 positive and negative group respectively. Because a large portion of patients were below the suggested 30\u00a0ng\/mL threshold, we can\u2019t exclude that VitD supplementation, restoring normal levels, might be beneficial in reducing the risk of infection. <\/jats:p>","DOI":"10.1024\/0300-9831\/a000687","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T13:11:53Z","timestamp":1604322713000},"page":"200-203","source":"Crossref","is-referenced-by-count":21,"title":["No significant association between vitamin D and COVID-19: A \t\t\t\t\tretrospective study from a northern Italian hospital"],"prefix":"10.31083","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7084-6800","authenticated-orcid":true,"given":"Davide","family":"Ferrari","sequence":"first","affiliation":[{"name":"SCVSA Department, University of Parma, \t\t\t\t\t\tParma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Locatelli","sequence":"additional","affiliation":[{"name":"Laboratory Medicine Service, San Raffaele Hospital, \t\t\t\t\t\tMilano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","reference":[{"key":"c1","unstructured":"Worldometers. COVID-19 coronavirus \t\t\t\t\t\tpandemic statistics [Internet]. [cited 2020 Sep 29]. \t\t\t\t\t\tAvailable from: https:\/\/www.worldometers.info\/coronavirus\/."},{"key":"c2","first-page":"M20\u20133012","author":"Oran DP","year":"2020","journal-title":"Ann Intern Med"},{"key":"c3","volume":"100618","author":"Zaim S","year":"2020","journal-title":"Curr Probl Cardiol"},{"issue":"1","key":"c4","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/s41392-020-00356-8","volume":"5","author":"Tan L","year":"2020","journal-title":"Signal Transduct Target Ther"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2020.06.021"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2020.04.050"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.3390\/nu12051359"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.11613\/BM.2017.030501"},{"key":"c9","volume":"5813095","author":"Rondanelli M","year":"2018","journal-title":"Evid Based Complement Alternat Med"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-020-01570-8"},{"key":"c11","first-page":"19","volume":"000","author":"Whittemore PB","year":"2020","journal-title":"Am J Infect Control"},{"key":"c12","first-page":"1438","volume":"51","author":"Garg M","year":"2020","journal-title":"Pharmacol Ther"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2018.04.038"},{"key":"c14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2019.02.037"},{"key":"c15","first-page":"1","volume":"55","author":"Guan WJ","year":"2020","journal-title":"Eur Respir J"},{"key":"c16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2010.04.002"},{"key":"c17","doi-asserted-by":"publisher","DOI":"10.1039\/c9pp00372j"},{"key":"c18","doi-asserted-by":"publisher","DOI":"10.1038\/s41430-020-0661-0"}],"container-title":["International Journal for Vitamin and Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0300-9831\/a000687","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T02:06:46Z","timestamp":1723169206000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/IJVNR\/91\/3-4\/10.1024\/0300-9831\/a000687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":18,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1024\/0300-9831\/a000687"],"URL":"https:\/\/doi.org\/10.1024\/0300-9831\/a000687","relation":{},"ISSN":["0300-9831","1664-2821"],"issn-type":[{"value":"0300-9831","type":"print"},{"value":"1664-2821","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6]]}}}