{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:02:25Z","timestamp":1723248145259},"reference-count":0,"publisher":"IMR Press","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Vitamin and Nutrition Research"],"published-print":{"date-parts":[[1999,1,1]]},"abstract":"<jats:p> A placebo-controlled, depletion-repletion protocol was utilized to examine the effect of vitamin C status on substrate utilization during a 90 min walk at 50% maximal oxygen consumption (VO2max). Nine vitamin C depleted subjects (plasma vitamin C &lt; 28 mumol\/L) agreed to participate in the 5-week study (aged, 27.6 \u00b1 2.5 years , mean \u00b1 SE; 5 females, 4 males). Subjects were apparently healthy but unaware of their vitamin C status. Prior to the experimental period, VO <jats:sub>2max<\/jats:sub> was measured using open-circuit spirometry during a graded walking protocol. Subjects ingested a placebo capsule daily during weeks 1\u20133 and a 500 mg vitamin C capsule daily during weeks 4\u20135 of the experimental study. Mean plasma vitamin C rose nearly 3-fold and mean plasma carnitine fell by nearly 20% at repletion (week 5) versus depletion (week 3). At the end of weeks 3 and 5, subjects completed a 90 minute treadmill walk at an exercise intensity of 50% VO<jats:sub>2max<\/jats:sub>. The relative contribution of fat utilized for energy during walking did not differ in the vitamin C depleted versus repleted states. However, work performed by subjects and gross efficiency during exercise increased significantly at repletion versus depletion (10% and 15%, respectively). These data indicate that vitamin C depletion is associated with reduced work efficiency during submaximal exercise. <\/jats:p>","DOI":"10.1024\/0300-9831.69.1.41","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:27:18Z","timestamp":1138710438000},"page":"41-44","source":"Crossref","is-referenced-by-count":11,"title":["Substrate Utilization and Work Efficiency during Submaximal Exercise in Vitamin C Depleted-Repleted Adults"],"prefix":"10.31083","volume":"69","author":[{"family":"Johnston","sequence":"first","affiliation":[{"name":"Department of Family Resources and Human Development, Arizona State University, Tempe, AZ 85287"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Swan","sequence":"additional","affiliation":[{"name":"Department of Exercise Science and Physical Education, Arizona State University, Tempe, AZ 85287"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Corte","sequence":"additional","affiliation":[{"name":"Department of Exercise Science and Physical Education, Arizona State University, Tempe, AZ 85287"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","container-title":["International Journal for Vitamin and Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0300-9831.69.1.41","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T02:14:45Z","timestamp":1723169685000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/IJVNR\/69\/1\/10.1024\/0300-9831.69.1.41"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,1,1]]}},"alternative-id":["10.1024\/0300-9831.69.1.41"],"URL":"https:\/\/doi.org\/10.1024\/0300-9831.69.1.41","relation":{},"ISSN":["0300-9831","1664-2821"],"issn-type":[{"type":"print","value":"0300-9831"},{"type":"electronic","value":"1664-2821"}],"subject":[],"published":{"date-parts":[[1999,1,1]]}}}