{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T09:37:37Z","timestamp":1783330657639,"version":"3.54.6"},"reference-count":0,"publisher":"IMR Press","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Vitamin and Nutrition Research"],"published-print":{"date-parts":[[2003,7,1]]},"abstract":"<jats:p> This study was carried out to determine how much of a single oral dose of beta-carotene in oil is absorbed and how much of the absorbed dose is converted to retinoids in rats having a vitamin A reserve at the lowest end of adequate status. Weanling rats raised on a vitamin A-deficient diet for four weeks were given a single oral dose of either corn oil or beta-carotene dissolved in corn oil (1.86 mumol). Serum, liver, and the entire digestive tract of the rats were analyzed for carotenoids and retinoids. Results showed that 4 hours after dosing, 1.64 mumol (88%) of the dose of beta-carotene was found intact, with 17.6% found in the stomach, 21% in the small intestine, and 49.3% in the large intestine. A total of 0.28 mumol of newly formed retinoids (expressed as retinyl palmitate) was present in serum, liver, and mucosa of small intestine. The results suggest that a single oral dose of beta-carotene might not be an effective way of raising vitamin A status in rats. <\/jats:p>","DOI":"10.1024\/0300-9831.73.4.267","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:28:47Z","timestamp":1138710527000},"page":"267-273","source":"Crossref","is-referenced-by-count":5,"title":["Absorption and Conversion of a Single Oral Dose of beta-Carotene in Corn Oil to Vitamin A in Sprague-Dawley Rats with Low Reserve of Vitamin A"],"prefix":"10.31083","volume":"73","author":[{"family":"Barua","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, IA 50011, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","container-title":["International Journal for Vitamin and Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0300-9831.73.4.267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T02:13:24Z","timestamp":1723169604000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/IJVNR\/73\/4\/10.1024\/0300-9831.73.4.267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,7,1]]}},"alternative-id":["10.1024\/0300-9831.73.4.267"],"URL":"https:\/\/doi.org\/10.1024\/0300-9831.73.4.267","relation":{},"ISSN":["0300-9831","1664-2821"],"issn-type":[{"value":"0300-9831","type":"print"},{"value":"1664-2821","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,7,1]]}}}