{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:54:56Z","timestamp":1791593696395,"version":"4.3.4"},"reference-count":0,"publisher":"IMR Press","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Vitamin and Nutrition Research"],"published-print":{"date-parts":[[2008,3,1]]},"abstract":"<jats:p> Background: Iron deficiency anemia (IDA) in the Philippines is a serious public health problem. Fortifying rice offers a great opportunity to control IDA. However, information on other types of fortificants that can be used is scarce. Objective: To compare the effects of two types of iron fortificants in rice in improving the hematological status of schoolchildren. Design: 180 randomly selected 6-to 9-year-old anemic children were randomly allocated to three groups in a double-blinded manner: One group received iron-enriched rice (IER) with extruded iron premix rice (IPR) using ferrous sulfate as fortificant (ExFeSO<jats:sub>4<\/jats:sub>); the second group received IER with extruded IPR using micronized dispersible ferric pyrophosphate (ExFeP80); and the third group received non-fortified rice (Control). These were administered daily for 5 days a week for 6 months. Blood samples were collected at baseline after 3 and 6 months. Results: At baseline, one child in the ExFeP80 group was suffering from IDA; at 3 months, no IDA was found in any groups; while at 6 months, one child in the ExFeP80 developed IDA. The baseline prevalence of anemia in all groups, which was 100%, was significantly reduced to 51%, 54%, and 63% in the ExFeSO<jats:sub>4<\/jats:sub>, ExFeP80 and Control groups respectively. After 6 months, further significant reductions were observed in the ExFeSO<jats:sub>4<\/jats:sub> (38%) and ExFeP80 (33%) but remained at 63% in the Control group. Greater, significant increases were also observed in plasma ferritin in the fortified groups than in the Control group from baseline to 6 months. The predictors of change in hemoglobin (Hb) and plasma ferritin were group allocation and basal values. Conclusion: The consumption of rice fortified with FeP80 using extrusion technology has similar effects as that of FeSO<jats:sub>4<\/jats:sub> in reducing the prevalence of IDA among schoolchildren. <\/jats:p>","DOI":"10.1024\/0300-9831.78.2.74","type":"journal-article","created":{"date-parts":[[2008,9,11]],"date-time":"2008-09-11T02:30:35Z","timestamp":1221100235000},"page":"74-86","source":"Crossref","is-referenced-by-count":41,"title":["Efficacy of Iron-Fortified Rice in Reducing Anemia Among Schoolchildren in the Philippines"],"prefix":"10.31083","volume":"78","author":[{"family":"Angeles-Agdeppa","sequence":"first","affiliation":[{"name":"1 From the Food and Nutrition Research Institute, Department of Science and Technology (IAA and MVC); Institute of Human Nutrition and Food, University of the Philippines Los Banos (CVCB); International Life Sciences Institute, Southeast Asia Region (RFF); International Life Sciences Institute Center for Health Promotion of Japan (KT) 2 Supported by International Life Sciences Institute Center for Health Promotion, Tokyo, Japan and International Life Sciences Institute Center for Health Promotion,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Capanzana","sequence":"additional","affiliation":[{"name":"1 From the Food and Nutrition Research Institute, Department of Science and Technology (IAA and MVC); Institute of Human Nutrition and Food, University of the Philippines Los Banos (CVCB); International Life Sciences Institute, Southeast Asia Region (RFF); International Life Sciences Institute Center for Health Promotion of Japan (KT) 2 Supported by International Life Sciences Institute Center for Health Promotion, Tokyo, Japan and International Life Sciences Institute Center for Health Promotion,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Barba","sequence":"additional","affiliation":[{"name":"1 From the Food and Nutrition Research Institute, Department of Science and Technology (IAA and MVC); Institute of Human Nutrition and Food, University of the Philippines Los Banos (CVCB); International Life Sciences Institute, Southeast Asia Region (RFF); International Life Sciences Institute Center for Health Promotion of Japan (KT) 2 Supported by International Life Sciences Institute Center for Health Promotion, Tokyo, Japan and International Life Sciences Institute Center for Health Promotion,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Florentino","sequence":"additional","affiliation":[{"name":"1 From the Food and Nutrition Research Institute, Department of Science and Technology (IAA and MVC); Institute of Human Nutrition and Food, University of the Philippines Los Banos (CVCB); International Life Sciences Institute, Southeast Asia Region (RFF); International Life Sciences Institute Center for Health Promotion of Japan (KT) 2 Supported by International Life Sciences Institute Center for Health Promotion, Tokyo, Japan and International Life Sciences Institute Center for Health Promotion,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Takanashi","sequence":"additional","affiliation":[{"name":"1 From the Food and Nutrition Research Institute, Department of Science and Technology (IAA and MVC); Institute of Human Nutrition and Food, University of the Philippines Los Banos (CVCB); International Life Sciences Institute, Southeast Asia Region (RFF); International Life Sciences Institute Center for Health Promotion of Japan (KT) 2 Supported by International Life Sciences Institute Center for Health Promotion, Tokyo, Japan and International Life Sciences Institute Center for Health Promotion,..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","container-title":["International Journal for Vitamin and Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0300-9831.78.2.74","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T02:11:14Z","timestamp":1723169474000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/IJVNR\/78\/2\/10.1024\/0300-9831.78.2.74"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,3,1]]}},"alternative-id":["10.1024\/0300-9831.78.2.74"],"URL":"https:\/\/doi.org\/10.1024\/0300-9831.78.2.74","relation":{},"ISSN":["0300-9831","1664-2821"],"issn-type":[{"value":"0300-9831","type":"print"},{"value":"1664-2821","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,1]]}}}