{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T21:13:13Z","timestamp":1694639593170},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2010,5,1]]},"abstract":"<jats:p> Background: Bicuspid aortic valve (BAV) is associated with an arteriopathy leading to a progressive dilatation of the aortic root. Recent studies have shown that the whole thoracic aorta is affected by this arteriopathy. Longitudinal data regarding the progression of this arteriopathy in the whole thoracic aorta has not been reported before. Patients and methods: In this retrospective study 40 patients (mean age 28.5 \u00b1 9.1 years) had 2 MR-angiographies (mean interval 37.1 \u00b1 15.2 months). In 23 patients the aortic valve was regurgitant, in 1 stenotic, in 4 combined aortic stenosis \/ regurgitation was found, while in 12 the valve function was normal. Aortic diameters were measured at 6 different, standardized anatomical points. The influence of demographic and clinical parameters was assessed. Results: A significant increase of the diameter was observed at the aortic root (35.4 \u00b1 5.6 mm \u2192 39.1 \u00b1 6.5 mm, p &lt; 0.001), the ascending aorta (37.3 \u00b1 8.0 mm \u2192 39.5 \u00b1 8.5 mm, p = 0.001), proximal to the innominate artery (29.4 \u00b1 6.1 mm \u2192 31.6 \u00b1 6.8 mm, p = 0.008), and the descending aorta (20.2 \u00b1 2.4 mm \u2192 21.6 \u00b1 4.2 mm, p = 0.03). There was no significant increase proximal (24.0 \u00b1 5.7 mm \u2192 24.6 \u00b1 5.3 mm, p = 0.44) and distal to the left subclavian artery (21.4 \u00b1 4.6 mm \u2192 21.9 \u00b1 4.5 mm, p = 0.19). These observations were independent of the presence of arterial hypertension, a previous operation, gender, and functional status of the aortic valve. Conclusions: The progressive dilatation of the aortic root and ascending aorta that can be observed in patients with BAV was not found in the more distal parts of the thoracic aorta with the exception of the descending aorta in this study. If the dilatation of the descending aorta bears any clinical significance can't be answered with the current data. A prospective study should be performed to confirm these results. <\/jats:p>","DOI":"10.1024\/0301-1526\/a000019","type":"journal-article","created":{"date-parts":[[2010,5,12]],"date-time":"2010-05-12T02:32:06Z","timestamp":1273631526000},"page":"140-144","source":"Crossref","is-referenced-by-count":1,"title":["Serial evaluation of the thoracic aorta in patients with a bicuspid aortic valve: A magnetic resonance angiography study"],"prefix":"10.1024","volume":"39","author":[{"family":"Tutarel","sequence":"first","affiliation":[{"name":"Medizinische Hochschule Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Meyer","sequence":"additional","affiliation":[{"name":"Medizinische Hochschule Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Lotz","sequence":"additional","affiliation":[{"name":"Medizinische Hochschule Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Westhoff-Bleck","sequence":"additional","affiliation":[{"name":"Medizinische Hochschule Hannover, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a000019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T11:46:56Z","timestamp":1652010416000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a000019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,5,1]]}},"alternative-id":["10.1024\/0301-1526\/a000019"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a000019","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,1]]}}}