{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:10:47Z","timestamp":1790925047404,"version":"4.1.0"},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2012,3,1]]},"abstract":"<jats:p> We have investigated the role of drug-eluting stents on patency rates after treatment of focal infrapopliteal lesions in patients with intermittent claudication and critical limb ischemia. Reports indicate that drug-eluting stents reduce the risk of restenosis after percutaneous infrapopliteal artery revascularization. A Pub Med, EMBASE, Cochrane database review search of non-randomized studies investigating patency rates, target lesion revascularisation rates, limb salvage rates and mortality rates in an up to 3-year follow-up period after drug-eluting stent placement was conducted. In addition, preliminary results of randomized studies comparing drug-eluting stents with bare-metal stents and plain balloon angioplasty in treatment of focal infrapopliteal lesions were included in this review. A total of 1039 patients from 10 non-randomized and randomized studies were included. Most commonly used drug-eluting stents were sirolimus-eluting. The mean follow-up period was 12.6 (range 8 - 24). The mean 1-year primary patency rate was 86 \u00b1 5 %. The mean target lesion revascularization rate and limb salvage rate was 9.9 \u00b1 5 % and 96.6 %\u00b14 %, respectively. Results from non-randomized and preliminary results from prospective, randomized trials show a significant advantage for drug-eluting stents in comparison to plain balloon angioplasty and bare-metal stents concerning target lesion patency and in parts target lesion revascularisation. No trial reveals an advantage for drug-eluting stents with regard to limb salvage and mortality. <\/jats:p>","DOI":"10.1024\/0301-1526\/a000170","type":"journal-article","created":{"date-parts":[[2013,2,2]],"date-time":"2013-02-02T02:21:20Z","timestamp":1359771680000},"page":"90-95","source":"Crossref","is-referenced-by-count":13,"title":["Drug-eluting stents for treatment of focal infrapopliteal lesions"],"prefix":"10.1024","volume":"41","author":[{"family":"Rastan","sequence":"first","affiliation":[{"name":"Herzzentrum Bad Krozingen, Bad Krozingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Noory","sequence":"additional","affiliation":[{"name":"Herzzentrum Bad Krozingen, Bad Krozingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Zeller","sequence":"additional","affiliation":[{"name":"Herzzentrum Bad Krozingen, Bad Krozingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"101","container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a000170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T11:51:16Z","timestamp":1652010676000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a000170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,3,1]]}},"alternative-id":["10.1024\/0301-1526\/a000170"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a000170","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,1]]}}}