{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:44:02Z","timestamp":1715604242714},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2013,3,1]]},"abstract":"<jats:p> Background: Variation in the ankle-brachial index (ABI) is related to the progression of atherosclerosis in the lower extremities and is associated with mid-term cardiovascular morbidity and mortality. The aim of this study was to investigate the changes in ABI after four years of follow-up of individuals in the general population, and the factors associated with relevant variations observed. Patients and methods: The study was performed in 750 volunteers (mean age 69.9 years) men without any evidence of peripheral artery disease, who attended a primary care centre. A complete physical examination, together with standard blood tests and ABI were performed. Four years later a new clinical evaluation was done. Variations in ABI values were considered relevant if &gt; 10 %. Results: Mean ABI in the second visit was 1.07 \u00b1 0.15, which represented 0.02 \u00b1 0.12 points lower than in the first visit (P &lt; 0.001). Of these subjects, 157 (21.6 %) had an ABI decrease &gt; 10 %. Multivariate analysis showed that the change was associated with male gender, cardiovascular history, no intake of blockers of the renin-angiotensin system, and the presence of atherogenic dyslipidaemia. A relevant increase in ABI was observed in 117 subjects (16.1 %), but was not associated with any of the studied factors. Conclusions: ABI values tend to decrease in the general population, although one sixth of the studied subjects had a relevant increase in this parameter. <\/jats:p>","DOI":"10.1024\/0301-1526\/a000254","type":"journal-article","created":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T02:19:44Z","timestamp":1363227584000},"page":"112-119","source":"Crossref","is-referenced-by-count":3,"title":["Differences in the ankle-brachial index in the general population after 4 years of follow-up"],"prefix":"10.1024","volume":"42","author":[{"given":"Carlos","family":"Lahoz","sequence":"first","affiliation":[{"name":"Hospital Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Garcia-Fernandez","sequence":"additional","affiliation":[{"name":"Centro de Salud Fuencarral, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Barrionuevo","sequence":"additional","affiliation":[{"name":"Centro de Salud Fuencarral, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Vicente","sequence":"additional","affiliation":[{"name":"Centro de Salud Fuencarral, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Gonzalez-Alegre","sequence":"additional","affiliation":[{"name":"Hospital Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M.","family":"Mostaza","sequence":"additional","affiliation":[{"name":"Hospital Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a000254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T10:31:24Z","timestamp":1615977084000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a000254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,3,1]]}},"alternative-id":["10.1024\/0301-1526\/a000254"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a000254","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,1]]}}}