{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:32:52Z","timestamp":1790188372271,"version":"4.1.0"},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2017,6,1]]},"abstract":"<jats:p> Abstract. Background: Despite ongoing research concerning comorbidities and clinical presentation of peripheral arterial disease (PAD), the issue of gender associated differences in treatment is far from being settled. Patients and methods: This was a prospective, non-randomized multicentre study design. All patients suffering from intermittent claudication (IC) or critical limb ischaemia (CLI) were included. Results: A total of 2,798 procedures for symptomatic PAD in the infrainguinal region were recorded, with 1,696 (61.4 %) males. Distribution of comorbidities for patients with IC were gender-specifically different. Smoking was more common in men (41.9 vs. 31.9 %, p &lt; .001), men had more often previous coronary heart disease (35.2 vs. 27.7 %, p = .007), and suffered more often from diabetes (33.9 vs. 28.2 %, p = .037). Women were generally older (71 vs. 77 years). Men were more prone to present with IC (46.9 vs. 43.6 %, p &lt; .001) and ulcer\/gangrene (43.6 vs. 41.2 %, p &lt; .001). Women were more likely to present with rest pain (9.5 vs. 15.1 %, p &lt; .001). Men were more often treated for a lesion below the knee (BTK) (21.1 vs. 14.9 %, p &lt; .001), and females above the knee (ATK) (58.1 vs. 61.5 %, p &lt; .001). Logistic regression analysis revealed a significant association of male gender and treatment for lesions BTK (OR 1.565, 95 % CI 1.281-1.913, p &lt; .001). Dissections and bleeding complications were more often observed in females with IC (3.3 vs. 7.2 %, p = 0.003; 0.4 vs. 1.5 %, p = 0.044). Women were rather discharged to rehabilitation and had a longer hospital stay compared to men (3.4 vs. 8.9 %, p &lt; .001; three vs. four days, p = .023). Conclusions: The present study provides an overview on gender-specific differences in endovascular treatment of PAD. To date, available evidence on this topic is limited, emphasising the importance of further vascular research targeting this topic. <\/jats:p>","DOI":"10.1024\/0301-1526\/a000634","type":"journal-article","created":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T16:41:04Z","timestamp":1493311264000},"page":"296-303","source":"Crossref","is-referenced-by-count":20,"title":["Gender differences in endovascular treatment of infrainguinal                     peripheral artery disease"],"prefix":"10.1024","volume":"46","author":[{"given":"Henrik Christian","family":"Rie\u00df","sequence":"first","affiliation":[{"name":"Department of Vascular Medicine,                     University Heart Center Hamburg, University Medical Center Hamburg-Eppendorf,                     Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eike Sebastian","family":"Debus","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine,                     University Heart Center Hamburg, University Medical Center Hamburg-Eppendorf,                     Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Heidemann","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine,                     University Heart Center Hamburg, University Medical Center Hamburg-Eppendorf,                     Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstanze","family":"Stoberock","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine,                     University Heart Center Hamburg, University Medical Center Hamburg-Eppendorf,                     Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhart T.","family":"Grundmann","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine,                     University Heart Center Hamburg, University Medical Center Hamburg-Eppendorf,                     Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian-Alexander","family":"Behrendt","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine,                     University Heart Center Hamburg, University Medical Center Hamburg-Eppendorf,                     Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"101","container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a000634","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T09:47:08Z","timestamp":1615974428000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a000634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,6,1]]}},"alternative-id":["10.1024\/0301-1526\/a000634"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a000634","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,1]]}}}