{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T08:54:20Z","timestamp":1770454460797,"version":"3.49.0"},"reference-count":20,"publisher":"Hogrefe Publishing Group","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2019,5,1]]},"abstract":"<jats:p> Abstract. Chronic critical lower limb ischemia (CLI) has been defined as ischemia that endangers the leg. An attempt was made to give a precise definition of CLI, based on clinical and hemodynamic data (Second European Consensus). CLI may be easily defined from a clinical point of view as rest pain of the distal foot or gangrene or ulceration. It is probably useful to add leg ulcers of other origin which do not heal because of severe ischemia, and to consider the impact of frailty on adverse outcome. From a hemodynamic viewpoint there is no consensus and most of the existing classifications are not based upon evidence. We should thus propose a definition and then validate it in a prospective cohort in order to define the patients at major risk of amputation, and also to define the categories of patients whose prognosis is improved by revascularisation. From today\u2019s available data, it seems clear that the patients with a systolic toe pressure (STP) below 30 mmHg must be revascularised whenever possible. However other patients with clinically suspected CLI and STP above 30 mmHg must be evaluated and treated in specialised vascular units and revascularisation has to be discussed on a case by case basis, taking into account other data such as the WiFi classification for ulcers.In conclusion, many useful but at times contradictory definitions of CLI have been suggested. Only a few have taken into account evidence, and none have been validated prospectively. This paper aims to address this and to give notice that a CLI registry within Europe will be set up to prospectively validate, or not, the previous and suggested definitions of CLI. <\/jats:p>","DOI":"10.1024\/0301-1526\/a000764","type":"journal-article","created":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T13:26:59Z","timestamp":1542634019000},"page":"223-227","source":"Crossref","is-referenced-by-count":23,"title":["Urgent need to clarify the definition of chronic critical limb                     ischemia \u2013 a position paper from the European Society for Vascular                     Medicine"],"prefix":"10.1024","volume":"48","author":[{"given":"Jo\u00ebl","family":"Constans","sequence":"first","affiliation":[{"name":"Service de M\u00e9decine Vasculaire,                     H\u00f4pital Saint-Andr\u00e9, Bordeaux ; Universit\u00e9 de Bordeaux, Bordeaux,                     France"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Bura-Rivi\u00e8re","sequence":"additional","affiliation":[{"name":"service de M\u00e9decine Vasculaire,                     H\u00f4pital Rangueil, Toulouse, France"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Visona","sequence":"additional","affiliation":[{"name":"Angiology Unit, Azienda ULSS 2 Marca                     Trevigiana, Castelfranco Veneto, Italy"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Brodmann","sequence":"additional","affiliation":[{"name":"Division of Angiology, Department of                     Internal Medicine, Medical University Graz, Graz, Austria"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Abraham","sequence":"additional","affiliation":[{"name":"Department of Physiology, University                     Hospital, Angers, France; LUNAM University, Inserm 1083\/CNRS 6015, Faculty                     of Medicine, Angers, France"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan-Mircea","family":"Olinic","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy,                     Emergency Hospital, Medical Clinic no. 1, Cluj-Napoca, Romania"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juraj","family":"Madaric","sequence":"additional","affiliation":[{"name":"Clinic of Cardiology and Angiology,                     National Cardiovascular Institute Bratislava, Slovakia"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Steiner","sequence":"additional","affiliation":[{"name":"Department of Interventional Angiology,                     Medical Faculty, University of Leipzig, Germany"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Qu\u00e9r\u00e9","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Vasculaire,                     H\u00f4pital Saint-Eloi, Montpellier, France"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Mazzolai","sequence":"additional","affiliation":[{"name":"Division of Angiology, Heart and Vessel                     Department, Lausanne; University Hospital, Lausanne, Switzerland"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill","family":"Belch","sequence":"additional","affiliation":[{"name":"The Institute of Cardiovascular                     Research, University of Dundee, Ninewells; Hospital and Medical School,                     Scotland, UK"},{"name":"ESVM writing group"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","first-page":"1","volume":"6","author":"Second European consensus document on chronic critical leg ischemia","year":"1992","journal-title":"Eur J Vasc Surg"},{"key":"c2","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1002\/bjs.1800691302","volume":"69","author":"Working Party of the International Vascular Symposium","year":"1982","journal-title":"Brit J Surg"},{"key":"c3","first-page":"737","author":"European consensus on critical limb ischemia","year":"1989","journal-title":"Lancet"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.1992.tb00523.x"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-821X(05)80260-9"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(97)70045-4"},{"key":"c7","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S0741-5214(00)81002-2","volume":"31","author":"Dormandy JA","year":"2000","journal-title":"J Vasc Surg"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"c9","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5884(11)60009-9"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1053\/j.semvascsurg.2014.12.002"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.01.040"},{"key":"c12","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X17701592"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx095"},{"key":"c14","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526\/a000432"},{"key":"c15","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.24.8.1433"},{"key":"c16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.08.026"},{"key":"c17","doi-asserted-by":"publisher","DOI":"10.1177\/0003319718793566"},{"key":"c18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2010.06.008"},{"key":"c19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.07.020"},{"key":"c20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.10.045"}],"container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a000764","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T01:00:00Z","timestamp":1615942800000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a000764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,1]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5,1]]}},"alternative-id":["10.1024\/0301-1526\/a000764"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a000764","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,1]]}}}