{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:23:06Z","timestamp":1791015786601,"version":"4.1.0"},"reference-count":16,"publisher":"Hogrefe Publishing Group","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:p> Summary: Background: Endovascular venous stenting with dedicated venous stents for the treatment of chronic venous outflow obstruction is developing as efficacious alternative to conservative therapy or open surgery. However, so far, mid- and long-term evidence on effectiveness and safety is poor. Patients and methods: The prospective, single-center, observational study enrolled consecutive patients with chronic non-thrombotic iliac vein lesions (NIVL) or post-thrombotic iliofemoral obstructions (PTO). From February 2016 to April 2017, patients underwent implantation of open cell, self-expandable dedicated venous stents. Short-term symptomatic improvement, patency, and complication rate were favorable. Evaluation at 2-years included improvement in the revised venous clinical severity score (rVCSS), patency, stent migration, major target limb events, clinically important pulmonary embolism, major bleeding, and all-cause mortality. Results: A total of 79 patients (57 \u00b1 16 years, 44 female) were evaluated. At 2 years, rVCCS improved by 4.3 \u00b1 2.7 (p &lt; 0.001). Substantial clinical improvement of \u2265 2 score points was achieved in 86.4% (38 of 44) of patients. Improvement was not associated with thrombotic pathogenesis (regression coefficient [B] with PTO = 0.6 [95%CI: \u22121.1 to 2.3], p = 0.48). At 2 years, all ulcers (in 8 of 79 patients) were healed and none recurred. Two-year primary patency was 95.5% (95%CI: 86.5 to 98.5) with no difference between NIVL- and PTO-patients (log-rank p = 0.83). Target vessel revascularization was conducted in two PTO- and one NIVL-patients in the period of 34 days to 156 days from index procedure, resulting in a secondary patency of 100%. No stent migration, target limb deep vein thrombosis, major amputation, pulmonary embolism, or death occurred. Conclusions: Venovo venous open cell self-expanding stent implantation for chronic outflow obstruction was efficacious and provided a sufficient level of safety throughout 2 years. <\/jats:p>","DOI":"10.1024\/0301-1526\/a000893","type":"journal-article","created":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T15:06:47Z","timestamp":1595430407000},"page":"52-58","source":"Crossref","is-referenced-by-count":23,"title":["Venovo venous stent for treatment of non-thrombotic or post-thrombotic iliac vein lesions \u2013 long-term efficacy and safety results from the Arnsberg venous registry"],"prefix":"10.1024","volume":"50","author":[{"given":"Michael K. 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