{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T19:22:11Z","timestamp":1788636131344,"version":"build-2803163510"},"reference-count":23,"publisher":"Hogrefe Publishing Group","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:p>Summary: Background: Our aim was to determine the rate of ischemic stroke following thoracic endovascular aortic repair (TEVAR) after reducing gas volume released during stentgraft deployment by de-airing of thoracic stentgrafts with high-volume of 0.9% heparinized saline solution. Patients and methods: A single center retrospective analysis of all consecutive patients undergoing TEVAR from 2014 to 2019 was performed. All thoracic stentgrafts were flushed with 120\u00a0ml 0.9% heparinized saline solution before implantation, according to our institutional protocol. Endpoints were in-hospital rates of ischemic stroke and spinal cord ischemia (SCI), and all-cause mortality. Results: One hundred and fifty-four patients (mean age: 66.8\u00a0\u00b1\u00a013.6\u00a0years, 64.9% males) were treated with TEVAR during the study period. Indications for treatment were thoracic aortic aneurysms (n\u00a0=\u00a075, 48.7%), acute type B aortic dissections (n\u00a0=\u00a046, 29.9%), aortic arch aneurysms and penetrating aortic ulcers (n\u00a0=\u00a028, 18.2%), and blunt traumatic aortic injuries (n\u00a0=\u00a05, 3.2%). Timing of procedure was urgent in 75 patients (48.7%). Proximal landing zone were zone 0\u20131\u20132 (n\u00a0=\u00a075, 48.7%), zone 3 (n\u00a0=\u00a066, 42.9%) and zone 4 (n\u00a0=\u00a013, 8.4%). Supra-aortic vessels were revascularized with custom-made fenestrated stentgrafts in 9 patients (5.8%), using chimney technique in 4 patients (2.6%), and with debranching procedures in 19 patients (12.3%). Left subclavian artery was covered without revascularization in 46 patients (29.9%). In-hospital stroke occurred in two patients (1.3%) and SCI in another two patients (1.3%). In-hospital mortality rate was 0.6%. No further in-hospital events were noted. Conclusions: De-airing of stentgrafts with high-volume of 0.9% heparinized saline solution seems to be safe and can be used as an adjunct to keep occurrence of neurological events after TEVAR as low as possible.<\/jats:p>","DOI":"10.1024\/0301-1526\/a000937","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T07:37:48Z","timestamp":1612856268000},"page":"186-192","source":"Crossref","is-referenced-by-count":6,"title":["Stroke rate after thoracic endovascular aortic repair using de-airing of stentgrafts with high-volume of saline solution"],"prefix":"10.1024","volume":"50","author":[{"given":"Daniela","family":"Branzan","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, University Hospital Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Geisler","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University Hospital Leipzig, 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