{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:35:28Z","timestamp":1792719328471,"version":"4.5.0"},"reference-count":21,"publisher":"Hogrefe Publishing Group","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p> Summary: Background: Treatment of pelvic venous disorders (PVD) including pelvic congestion syndrome (PCS) are often delayed due to its varying clinical manifestations. Patients and methods: Patient referral was based on a literature- and personal experience-derived clinical \u201cPCS screening score\u201d (higher score points indicate greater likelihood with a maximum score of 10 points). We studied consecutive women who were (i) referred for vascular assessment and treatment to the University Hospital Zurich (2017\u20132021), (ii) had a PCS score \u22653 points, (iii) had evidence of obstructive or non-obstructive PVD by duplex sonography or cross-sectional imaging, and (iv) underwent endovascular therapy. The primary outcome was change in symptom severity after endovascular therapy: (i) freedom from symptoms, (ii) improvement with residual symptoms, (iii) no improvement. Results: We included 43 women (mean age 36 years): 81% had previous pregnancy, 19% endometriosis. The median PCS score was 7 (IQR 5\u20139) points. Chronic lower-abdominal pain was the leading symptom in 86% patients, followed by recurrent leg (9%) and vulvar (5%) varicosities. The main PVD pathologies were ovarian vein insufficiency (61%), internal iliac vein insufficiency (9%), or a combination of both (30%), whereas 42% had a deep venous obstruction of the inferior vena cava, common iliac or left renal veins. Endovascular therapy included ovarian vein embolization (86%), internal iliac vein embolization (9%), and venous stent placement (35%). After a median of 4 (IQR 1\u20138) months from endovascular treatment, 40 (93%) patients reported improvement of the leading symptom, and 14 (33%) were symptom-free. Complications included re-intervention for stent stenosis (13%, all post-thrombotic), coil-migration into the left renal vein (7%, all retrieved), and transient pelvic sclerotherapy-induced thrombophlebitis (2%). Conclusions: Endovascular therapy following a diagnostic approach, which included a PCS screening tool and non-invasive imaging, appeared to be highly effective and was associated with a low rate of complications. <\/jats:p>","DOI":"10.1024\/0301-1526\/a001001","type":"journal-article","created":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T07:00:02Z","timestamp":1649833202000},"page":"182-189","source":"Crossref","is-referenced-by-count":16,"title":["A novel management strategy for treatment of pelvic venous disorders \t\t\t\t\tutilizing a clinical screening score and non-invasive imaging"],"prefix":"10.1024","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4013-2211","authenticated-orcid":true,"given":"Julia","family":"Neuenschwander","sequence":"first","affiliation":[{"name":"Medical Faculty, University of Zurich, \t\t\t\t\t\tSwitzerland"},{"name":"Department of Angiology, University Hospital Zurich, \t\t\t\t\t\tSwitzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Sebastian","sequence":"additional","affiliation":[{"name":"Department of Angiology, University Hospital Zurich, \t\t\t\t\t\tSwitzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Barco","sequence":"additional","affiliation":[{"name":"Department of Angiology, University Hospital Zurich, \t\t\t\t\t\tSwitzerland"},{"name":"Center for Thrombosis and Hemostasis, Johannes \t\t\t\t\tGutenberg University Mainz, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Spirk","sequence":"additional","affiliation":[{"name":"Institute of Pharmacology, University of Bern, \t\t\t\t\t\tSwitzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Kucher","sequence":"additional","affiliation":[{"name":"Department of Angiology, University Hospital Zurich, \t\t\t\t\t\tSwitzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.5.931"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2014\/17\/E141"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.23736\/S0392-9590.19.04237-8"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526\/a000946"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1258\/phleb.2011.012s07"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2016.01.002"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1177\/0268355514568067"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2017.09.011"},{"key":"c9","doi-asserted-by":"publisher","DOI":"10.1177\/0268355515569129"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2015.01.003"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.10.008"},{"key":"c12","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2013.09.011"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-013-0586-2"},{"key":"c14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2007.11.006"},{"key":"c15","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-008-9402-9"},{"issue":"1","key":"c16","first-page":"1","volume":"87","author":"d\u2019Archambeau O","year":"2004","journal-title":"JBR-BTR"},{"key":"c17","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.201.131"},{"key":"c18","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(07)61935-6"},{"key":"c19","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-007-9040-7"},{"key":"c20","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000194870.11980.F8"},{"key":"c21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2012.04.021"}],"container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a001001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T13:52:39Z","timestamp":1651499559000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a001001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1024\/0301-1526\/a001001"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a001001","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}