{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:40:08Z","timestamp":1762522808776,"version":"3.40.5"},"reference-count":33,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p> Summary: Background: Cardiovascular abnormalities have been described in patients with schistosomiasis. Their true prevalence and clinical features in endemic settings are unknown. Patients and methods: The study aimed to assess the prevalence of subclinical cardiovascular damage in a population endemic to schistosomiasis. A cross-sectional study was conducted using colour-ultrasound assessment of abdominal and carotid arteries among adults aged &gt;18 years living in Kome Island, Tanzania. Carotid intimal medial thickness, carotid plaque, mean abdominal aortic diameter, and presence of aneurysms were assessed. Anamnestic data on previous Schistosoma infection was collected; the actual prevalence of Schistosoma mansoni and Schistosoma haematobium was also assessed through stool and urine investigations. Results: A total of 264 participants (166 female, 98 male) were enrolled (mean age of 50\u00b115.5 years). The history of previous schistosomiasis was 27.3%, and actual positivity for Schistosoma mansoni was 5.9%. The Latero-lateral Abdominal Aortic Diameter was significantly increased among participants with a previous history of schistosomiasis (16.7\u00b12.8 mm vs. 17.6\u00b13\u00a0mm; p=0.02), with an aOR of 1.15 [CI 1.04\u20131.28]; p=0.007]. Conclusions: The significant difference in the Latero-lateral Abdominal Aortic Diameter in participants with a previous history of schistosomiasis suggests the need for further investigations on aortic damage in endemic populations, independently from the positive laboratory investigations. <\/jats:p>","DOI":"10.1024\/0301-1526\/a001069","type":"journal-article","created":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T08:06:57Z","timestamp":1679472417000},"page":"275-283","source":"Crossref","is-referenced-by-count":3,"title":["Subclinical vascular damage in Schistosoma spp. endemic \t\t\t\t\tregions"],"prefix":"10.1024","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1560-1530","authenticated-orcid":true,"given":"Valeria","family":"Silvestri","sequence":"first","affiliation":[{"name":"Department of Parasitology and Medical Entomology, \t\t\t\t\tMuhimbili University of Health and Applied Science, Dar es Salaam, 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