{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:19:42Z","timestamp":1762957182319,"version":"3.40.5"},"reference-count":67,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p>Summary: Background: Atherosclerotic disease of erection-related arteries is a major reason for erectile dysfunction (ED). Lp(a) has been implied in the pathophysiology of atherosclerosis in the coronary and lower limb arteries. Here, we investigated if Lp(a) plays a specific role in ED due with symptomatic pelvic artery atherosclerosis. Patients and methods: Out of 276 consecutive patients treated for ED with angioplasties on proximal (69%) and distal (31%, distal to Alcock channel) erection-related arteries, 236 patients (age: 62\u00b110 years) of which Lp(a) values were available were retrospectively analyzed. Results: The baseline International Index of Erectile Function-15 (IIEF-15) score was 29\u00b115 and significantly increased to 43\u00b120 (increase: 14\u00b121) after treatment at average follow up of 286\u00b1201 days. In 25%, Lp(a) values were elevated to more than 30 mg\/dL. Hypercholesterolemia, coronary, lower extremity peripheral, and polyvascular disease were more common in patients with Lp(a) \u226560 mg\/dl. Anatomic arterial lesion distribution (proximal\/distal), improvement in IIEF-15 and clinically driven re-intervention rate (overall 7%) did not differ between patients with &lt;30, 30\u201359, and \u226560 mg\/dL Lp(a). Conclusions: While angioplasty is an effective therapy for ED of arterial origin in patients with obstruction of erection-related arteries, Lp(a) does not seem to play a major role for clinical outcomes in these patients.<\/jats:p>","DOI":"10.1024\/0301-1526\/a001072","type":"journal-article","created":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T07:05:16Z","timestamp":1682924716000},"page":"230-238","source":"Crossref","is-referenced-by-count":2,"title":["Role of Lp(a) in patients with erectile dysfunction undergoing angioplasty for symptomatic pelvic artery disease"],"prefix":"10.1024","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5089-0759","authenticated-orcid":true,"given":"Christoph","family":"Kalka","sequence":"first","affiliation":[{"name":"Marienhospital Bruehl, Germany"},{"name":"Faculty of Medicine, University of Cologne, Germany"},{"name":"Vascular Institute Central Switzerland, Aarau, 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