{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T22:12:14Z","timestamp":1780524734870,"version":"3.54.1"},"reference-count":28,"publisher":"Hogrefe Publishing Group","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p> Summary: Background: Knowledge of factors that influence all-cause mortality after endovascular abdominal aortic aneurysm repair (EVAR) could improve therapeutic strategies post-EVAR and thus patient prognosis. Our study aimed to evaluate the association between sociodemographic information, comorbidities, laboratory parameters, treatment, selected anatomical and genetic factors and all-cause mortality post-EVAR. Patients and methods: We reviewed all patients who had undergone elective EVAR for non-ruptured abdominal aortic aneurysm (AAA) between January 2010 and December 2019. AAA size (maximum diameter and volume) was measured using CT-angiography. Sac expansion was defined as at least 5 mm increase, sac regression as at least 5 mm decrease in the sac diameter determined at 36\u00b13 months post-EVAR in relation to pre-EVAR AAA diameter. Adjustments were performed for age, hypertension, diabetes mellitus, dyslipidaemia, sex, smoking, number of lumbar arteries, patency of inferior mesenteric artery and number of reinterventions post-EVAR. Results: One hundred and sixty-two patients (150 men, 12 women) with a mean age of 72.6\u00b17.3 years were included in the analysis. Pre-EVAR AAA diameter (HR 1.07; 95% CI 1.03 \u2013 1.12; p=0.001), pre-EVAR AAA volume (HR 1.01; 95% CI 1.002 \u2013 1.011; p=0.008), post-EVAR sac diameter (HR 1.06; 95% CI 1.03 \u2013 1.10; p=0.000), post-EVAR sac volume (HR 1.01; 95% CI 1.002 \u2013 1.011; p=0.006) and anticoagulation therapy (HR 2.46; 95% CI 1.18 \u2013 5.14; p=0.019) were associated with higher mortality in multivariate analysis. Sac regression (HR 0.42; 95% CI 0.22 \u2013 0.82; p=0.011), and treatment with angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs) (HR 0.71; 95% CI 0.36 \u2013 0.97; p=0.047) were associated with lower mortality. Conclusions: Greater pre- and post-EVAR diameter and volume, failure of sac regression and anticoagulation were associated with higher mortality post-EVAR. Reduced mortality was observed in patients treated with ACE inhibitors or ARBs, and in patients with AAA sac regression. <\/jats:p>","DOI":"10.1024\/0301-1526\/a001081","type":"journal-article","created":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T10:30:12Z","timestamp":1687516212000},"page":"325-331","source":"Crossref","is-referenced-by-count":9,"title":["Factors associated with all-cause mortality following endovascular abdominal aortic aneurysm repair"],"prefix":"10.1024","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1848-3875","authenticated-orcid":true,"given":"M\u00e1ria","family":"Ra\u0161iov\u00e1","sequence":"first","affiliation":[{"name":"Department of Angiology, Faculty of Medicine, East Slovak Institute of Cardiovascular Diseases, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Ko\u0161\u010do","sequence":"additional","affiliation":[{"name":"Department of Angiology, Faculty of Medicine, East Slovak Institute of Cardiovascular Diseases, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matej","family":"Mo\u0161\u010dovi\u010d","sequence":"additional","affiliation":[{"name":"Department of Angiology, Faculty of Medicine, East Slovak Institute of Cardiovascular Diseases, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Pavl\u00edkov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Angiology, Faculty of Medicine, East Slovak Institute of Cardiovascular Diseases, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viera","family":"Habalov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Medicine Biology, Faculty of Medicine, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jozef","family":"\u017didzik","sequence":"additional","affiliation":[{"name":"Department of Medicine Biology, Faculty of Medicine, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuzana","family":"Tormov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Angiology, Faculty of Medicine, East Slovak Institute of Cardiovascular Diseases, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Hud\u00e1k","sequence":"additional","affiliation":[{"name":"Department of Angiology, Faculty of Medicine, East Slovak Institute of Cardiovascular Diseases, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Bavo\u013e\u00e1rov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Cardiology, \u0160tefan Kukura Hospital, Michalovce, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Slavom\u00edr","family":"Pere\u010dinsk\u00fd","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine and Clinical Toxicology, Faculty of Medicine, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Dekanov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Angiology, Faculty of Medicine, East Slovak Institute of Cardiovascular Diseases, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Tk\u00e1\u010d","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine 4, Faculty of Medicine, University of Pavol Jozef \u0160af\u00e1rik, Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31135-7"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.08.046"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.118.312439"},{"issue":"1","key":"c4","doi-asserted-by":"crossref","first-page":"e000054","DOI":"10.1136\/bmjsit-2020-000054","volume":"2","author":"Blakeslee-Carter J","year":"2020","journal-title":"BMJ Surg Interv Health Technol"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.01.027"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.123763"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.308765"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2019.02.017"},{"key":"c9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.118.312436"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddz256"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.07.082"},{"key":"c12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.10.067"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.10.093"},{"key":"c14","doi-asserted-by":"publisher","DOI":"10.1177\/1526602820937432"},{"key":"c15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.04.050"},{"key":"c16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2013.12.009"},{"key":"c17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2022.01.125"},{"key":"c18","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-019-0675-0"},{"key":"c19","author":"Isselbacher EM","journal-title":"Circulation"},{"key":"c20","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu281"},{"key":"c21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.09.020"},{"key":"c22","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e4260"},{"key":"c23","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs075"},{"key":"c24","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.119.13197"},{"key":"c25","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab368"},{"key":"c26","doi-asserted-by":"publisher","DOI":"10.1111\/eci.12173"},{"key":"c27","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.11238"},{"key":"c28","first-page":"9","volume":"1","author":"Cao RY","year":"2010","journal-title":"Front Pharmacol"}],"container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a001081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T07:01:47Z","timestamp":1693810907000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a001081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1024\/0301-1526\/a001081"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a001081","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]}}}