{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:57:22Z","timestamp":1791410242795,"version":"4.3.3"},"reference-count":30,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p> Summary: Background: Patients having emergency surgery due to ischemia caused by a popliteal artery aneurysm (PAA) have worse outcomes in all endpoints (operation time, major adverse limb events (MALE), amputation-free survival) than after elective treatment, mostly due to a limited crural vessel runoff. This study investigates the relationship between PAA diameter, volume, and luminal thrombus load in relation to the preoperative crural runoff. Patients and methods: Retrospective single-centre evaluation of surgically treated patients with PAA and semi-automated quantitative CT analysis of PAA morphologies (diameter, volume and intraluminal thrombus volume). Primary endpoints were the correlations these characteristics with the number of patent crural vessels. Results: A total of 89 PAAs (61 patients, median age 75, IQR 12; 94.4% male) were identified, of which 47.2% were symptomatic with 18 acute limb ischemia (ALI). The diameter at surgery was 33.8 \u00b1 12.1mm and the volume 68.5 \u00b1 13.6mm<jats:sup>3<\/jats:sup>. A median of two lower leg vessels were patent (elective 3 [ 1 , 2 , 3 ] vs. emergency 1 [ 1 , 2 ], p=0.1) upon preoperative CTA. 77 PAAs underwent elective surgery, five PAAs (5.6%) received endovascular treatment. The surgical complication rate was 23.6% without immediate or early occlusion. The follow-up was 42.5 [39\u201345] months. The overall mortality rate was 11.2% and the primary patency rate 73.9%. While the total aneurysm volume correlated well with the diameter (r=0.77, p&lt;0.01), the intraluminal thrombus volume (ILT) showed the clearest correlation with the crural runoff (r=\u20130.34, p=0.01). No correlation between the diameter and crural runoff was observed (r=\u20130.17, p=0.1). A reduced crural run-off was significantly associated with impaired amputation-free survival (p=0.01). A subgroup analysis (n=21) with sequential CTs showed a tendency towards greater increase of thrombus volume compared to plain diameter during PAA growth. The thrombus volume index (=ILT\/total PAA volume) was significantly higher in emergency patients (p=0.01), while diameters tended to be smaller (p=0.57). Conclusions: The increasing intraluminal thrombus volume correlates most distinctly with a reduced crural runoff in PAAs and should therefore be considered prognostically important, especially in the presence of an increased growth rate compared to the diameter. <\/jats:p>","DOI":"10.1024\/0301-1526\/a001198","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T15:33:06Z","timestamp":1744903986000},"page":"242-252","source":"Crossref","is-referenced-by-count":4,"title":["Intraluminal thrombus volume correlates with the crural vessel runoff in popliteal artery aneurysms upon initial presentation"],"prefix":"10.1024","volume":"54","author":[{"given":"Hans-Christian Arne","family":"Stroth","sequence":"first","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department for Visceral-, Thoracic and Vascular Surgery, Medical Faculty Carl Gustav Carus and University Hospital, Technische Universit\u00e4t Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Floris","family":"Berg","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department for Visceral-, Thoracic and Vascular Surgery, Medical Faculty Carl Gustav Carus and University Hospital, Technische Universit\u00e4t Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah Emilia","family":"Freytag","sequence":"additional","affiliation":[{"name":"Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Reeps","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department for Visceral-, Thoracic and Vascular Surgery, Medical Faculty Carl Gustav Carus and University Hospital, Technische Universit\u00e4t Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Wolk","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department for Visceral-, Thoracic and Vascular Surgery, Medical Faculty Carl Gustav Carus and University Hospital, Technische Universit\u00e4t Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3150-4263","authenticated-orcid":true,"given":"Ralf-Thorsten","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Institute and Polyclinic for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7303-6691","authenticated-orcid":true,"given":"Heiner","family":"Nebelung","sequence":"additional","affiliation":[{"name":"Institute and Polyclinic for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens-Peter","family":"K\u00fchn","sequence":"additional","affiliation":[{"name":"Institute and Polyclinic for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2374-0338","authenticated-orcid":true,"given":"Albert","family":"Busch","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department for Visceral-, Thoracic and Vascular Surgery, Medical Faculty Carl Gustav Carus and University Hospital, Technische Universit\u00e4t Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2649-4082","authenticated-orcid":true,"given":"Marvin","family":"Kapalla","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department for Visceral-, Thoracic and Vascular Surgery, Medical Faculty Carl Gustav Carus and University Hospital, Technische Universit\u00e4t Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1136\/jms.9.2.92"},{"issue":"3","key":"c2","first-page":"293","volume":"84","author":"Dawson I","year":"1997","journal-title":"Br J Surg"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2021.04.040"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2005.11.026"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1067\/mva.1991.26737"},{"issue":"6","key":"c6","first-page":"1009","volume":"90","author":"Vermilion BD","year":"1981","journal-title":"Surgery"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2012.07.004"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800811035"},{"key":"c9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2011.02.007"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2003.232"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2021.07.243"},{"key":"c12","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13102817"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.11.051"},{"key":"c14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2021.09.046"},{"key":"c15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvssci.2022.10.004"},{"key":"c16","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"c17","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2000.105955"},{"key":"c18","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800720708"},{"key":"c19","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(97)70045-4"},{"key":"c20","volume-title":"Statistical power analysis for the behavioral sciences","author":"Cohen J","year":"1988","edition":"2"},{"key":"c21","doi-asserted-by":"publisher","DOI":"10.1007\/BF02133401"},{"key":"c22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2005.05.021"},{"key":"c23","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.05.033"},{"key":"c24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2020.12.062"},{"key":"c25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2013.01.012"},{"key":"c26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.07.117"},{"issue":"6","key":"c27","first-page":"386","volume":"52","author":"M\u00fcller AM","year":"2023","journal-title":"Vasa"},{"key":"c28","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526\/a001121"},{"key":"c29","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526\/a001050"},{"key":"c30","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X231215781"}],"container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a001198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T07:44:12Z","timestamp":1751269452000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a001198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1024\/0301-1526\/a001198"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a001198","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]}}}