{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T08:25:23Z","timestamp":1775291123308,"version":"3.50.1"},"reference-count":26,"publisher":"Hogrefe Publishing Group","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p> Summary: Background: Lower limb peripheral artery disease (PAD) is a common manifestation of atherosclerosis, ranging from subclinical to severe stages including critical ischemia and amputation. Data on epidemiology of PAD in Africa are scarce. This study aimed to determine the prevalence of PAD and identify associated cardiovascular risk factors in Gabon\u2019s general population. Patients and methods: Our cross-sectional study utilized quota sampling in three municipalities of the Estuaire province in Gabon. We selected 1502 urban residents aged 18 years and older. Sociodemographic and behavioural data were collected using a questionnaire, along with the Edinburgh Claudication Questionnaire. Ankle-brachial index (ABI) was measured using Doppler examination. PAD was defined as an ABI \u2264 0.90. Results: The average age of the population was 45.2\u00b116.23 years, with 55.7% being females. Among participants, 299 (25.7%) had PAD (95% CI: 23.2\u201328.3). The prevalence of PAD was 26.2% (95% CI: 22.3\u201330.2) among men and 25.3% (95% CI: 22.0\u201328.7) among women. Among the PAD cases, 35 subjects (11.7%) were symptomatic. In the multivariate analysis, factors significantly associated with PAD were sedentary lifestyle (OR = 1.4; 95% CI: 1.0\u20131.8), hypertension (OR=1.3; 1.0\u20131.7) and being overweight (OR = 1.8; 95% CI: 1.1\u20133.1), grade 1 obesity (OR = 1.7; 95% CI: 1.0\u20132.9), and grade 2 obesity (OR = 1.9; 95% CI: 1.1\u20133.2) Conclusions: The prevalence of lower limb PAD in Gabon\u2019s urban population is important. This highlights the need for greater awareness among those with high cardiovascular risk and mandatory screening in health facilities. <\/jats:p>","DOI":"10.1024\/0301-1526\/a001200","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T02:04:18Z","timestamp":1748397858000},"page":"354-360","source":"Crossref","is-referenced-by-count":2,"title":["Epidemiology of lower limb peripheral artery disease in urban areas of the Estuaire Province, Gabon"],"prefix":"10.1024","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5044-0947","authenticated-orcid":true,"given":"Marie Jocelyne","family":"Kouna Oumoyi Doumbeneny","sequence":"first","affiliation":[{"name":"Inserm U1094, IRD U270, University of Limoges, Limoges University Hospital, EpiMaCT \u2013 Epidemiology of Chronic Diseases in Tropical Zones, Institute of Epidemiology and Tropical Neurology, OmegaHealth, Limoges, France"},{"name":"Department of Epidemiology, Biostatistics, and Medical Informatics (DEBIM), Research Unit in Chronic Disease Epidemiology and Environmental Health, University of Health Sciences, Libreville, Gabon"},{"name":"Regional Doctoral School of Central Africa in Tropical Infectiology, Franceville, Gabon"},{"name":"Department of Medicine, Biomedical Research and Hospital Information Service, Omar Bongo Ondimba Military Teaching Hospital, University of Health Sciences and Technology, Libreville, Gabon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1692-3937","authenticated-orcid":true,"given":"Euloge","family":"Ibinga","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Biostatistics, and Medical Informatics (DEBIM), Research Unit in Chronic Disease Epidemiology and Environmental Health, University of Health Sciences, Libreville, Gabon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7632-0707","authenticated-orcid":true,"given":"Jean Leonard","family":"Mbini Junior","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cardiology Service, Omar Bongo Ondimba Military Teaching Hospital, University of Health Sciences and Technology, Libreville, Gabon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9504-3094","authenticated-orcid":true,"given":"Edgard Brice","family":"Ngoungou","sequence":"additional","affiliation":[{"name":"Inserm U1094, IRD U270, University of Limoges, Limoges University Hospital, EpiMaCT \u2013 Epidemiology of Chronic Diseases in Tropical Zones, Institute of Epidemiology and Tropical Neurology, OmegaHealth, Limoges, France"},{"name":"Department of Epidemiology, Biostatistics, and Medical Informatics (DEBIM), Research Unit in Chronic Disease Epidemiology and Environmental Health, University of Health Sciences, Libreville, Gabon"},{"name":"Regional Doctoral School of Central Africa in Tropical Infectiology, Franceville, Gabon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Raymond","family":"Nzenze","sequence":"additional","affiliation":[{"name":"Department of Medicine, Omar Bongo Ondimba Military Teaching Hospital, University of Health Sciences and Technology, Libreville, Gabon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0322-9818","authenticated-orcid":true,"given":"Victor","family":"Aboyans","sequence":"additional","affiliation":[{"name":"Inserm U1094, IRD U270, University of Limoges, Limoges University Hospital, EpiMaCT \u2013 Epidemiology of Chronic Diseases in Tropical Zones, Institute of Epidemiology and Tropical Neurology, OmegaHealth, Limoges, France"},{"name":"Department of Cardiology, Dupuytren University Hospital Centre of Limoges, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(19)30318-3"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anchir.2005.03.008"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwad381"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1177\/1538574418784709"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.05.099"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1177\/2047487314557945"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2019.12.028"},{"key":"c8","first-page":"1","volume":"63","author":"Ona Ondo D","year":"2015","journal-title":"Direction G\u00e9n\u00e9rale de la Statistique"},{"key":"c9","unstructured":"Organisation Mondiale de la Sant\u00e9. Le Manuel de surveillance STEPS de l\u2019OMS: L\u2019approche STEPwise de l\u2019OMS pour la surveillance des facteurs de risque des maladies chroniques. Gen\u00e8ve: Organisation mondiale de la Sant\u00e9; 2005."},{"issue":"10","key":"c10","first-page":"1173","volume":"93","author":"Aboyans V","year":"2000","journal-title":"Arch Mal Coeur Vaiss"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e318276fbcb"},{"key":"c12","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/25.6.1172"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526\/a000871"},{"key":"c14","first-page":"48","volume":"351","author":"Emdin CA","year":"2015","journal-title":"BMJ"},{"key":"c15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ancard.2016.04.026"},{"key":"c16","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-10-38"},{"key":"c17","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2019.10.017"},{"key":"c18","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2013.04.030"},{"issue":"4","key":"c19","first-page":"189","volume":"5","author":"Lu JT","year":"2004","journal-title":"Rev Cardiovasc Med"},{"key":"c20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2004.08.049"},{"key":"c21","doi-asserted-by":"publisher","DOI":"10.1186\/s13690-022-00881-8"},{"key":"c22","unstructured":"World Health Organization. WHO global report on trends in prevalence of tobacco use 2000\u20132030. World Health Organization, 2024."},{"key":"c23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmv.2012.05.003"},{"key":"c24","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X19867393"},{"key":"c25","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000086882.59112.9d"},{"key":"c26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2012.05.019"}],"container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526\/a001200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T06:26:45Z","timestamp":1756708005000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526\/a001200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1024\/0301-1526\/a001200"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526\/a001200","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]}}}