{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T21:33:19Z","timestamp":1766179999490},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2002,11,1]]},"abstract":"<jats:p> Background: Examination of the influence of dorzolamide on the autoregulation of retinal vessel diameter in glaucoma patients. Patients and methods: Eleven patients with primary open angle glaucoma (age 60 \u00b1 11) without medication and four weeks after starting therapy with dorzolamid eye drops three times daily were examined in the study. Short-time rise of intraocular pressure (IOP) was obtained via suction-cup. Functional reaction of the diameter of a segment of a retinal artery and corresponding vein were assessed by retinal vessel analyzer. Results: Dorzolamid lowered the IOP from 23.3 \u00b1 1.3 to 17.6 \u00b1 2.2 mmHg (p = 0.004). Therapy did not influence the absolute diameter of retinal vessels regarding maximal dilatation caused by the pressure rising provocation. In eyes with treatment the diameter decreased faster to baseline values (arteries 100 sec, veins 220 sec) compared to those without treatment (arteries 350 sec, veins 480 sec). Conclusion: Dorzolamid might possibly be able to accelerate autoregulation of retinal vessels in response to short term artificial IOP increase. <\/jats:p>","DOI":"10.1024\/0301-1526.31.4.230","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:26:11Z","timestamp":1138710371000},"page":"230-234","source":"Crossref","is-referenced-by-count":7,"title":["Funktionsanalyse des Netzhautgef\u00e4\u00dfdurchmessers bei artifizieller Augeninnendrucksteigerung bei Glaukompatienten mit und ohne Therapie mit Dorzolamide"],"prefix":"10.1024","volume":"31","author":[{"family":"Nagel","sequence":"first","affiliation":[{"name":"Ophthalmic Private Practice, Rudolfstadt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Vilser","sequence":"additional","affiliation":[{"name":"Technical University, Ilmenau, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Lanzl","sequence":"additional","affiliation":[{"name":"Eye Department of the Technical University Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526.31.4.230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T09:53:29Z","timestamp":1652003609000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526.31.4.230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,11,1]]}},"alternative-id":["10.1024\/0301-1526.31.4.230"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526.31.4.230","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,11,1]]}}}