{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T18:52:36Z","timestamp":1694631156446},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasa"],"published-print":{"date-parts":[[2007,8,1]]},"abstract":"<jats:p> Background: To evaluate the timecourse of cerebrovascular reserve response to breath-holding. Patients and methods: Using simultaneous bilateral transcranial Doppler (TCD) recordings from the MCA during a breath-holding challenge, we measured the time interval between baseline and peak blood flow velocity values in 25 patients with critical unilateral internal carotid artery (ICA) stenosis (&gt; 85% lumen diameter reduction), in 9 patients with a non-critical (70\u201385%) ICA-stenosis and in 27 normal controls. Results: Normal controls and patients with non-critical stenosis reached peak MCA velocities on both sides almost simultaneously. For the patients with critical stenosis the peak response time ipsilateral to the stenosis was delayed 2.40 \u00b1 3.43 sec compared to the opposite side. This delay resolved after carotid endarterectomy. Conclusions: In response to a breath-holding challenge unilateral critical ICA stenosis is associated with a significant ipsilateral prolongation of the rise time from baseline to peak MCA velocity. <\/jats:p>","DOI":"10.1024\/0301-1526.36.3.181","type":"journal-article","created":{"date-parts":[[2007,8,20]],"date-time":"2007-08-20T02:30:09Z","timestamp":1187577009000},"page":"181-184","source":"Crossref","is-referenced-by-count":0,"title":["Cerebrovascular response time to a breath-holding challenge"],"prefix":"10.1024","volume":"36","author":[{"family":"Gahn","sequence":"first","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Neurologie, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Hallmeyer-Elgner","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Neurologie, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Becker","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Neurologie, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Barrett","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Neurologie, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Ackermann","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Neurologie, Universit\u00e4tsklinikum Carl Gustav Carus der Technischen Universit\u00e4t Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Vasa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0301-1526.36.3.181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T11:42:36Z","timestamp":1652010156000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0301-1526.36.3.181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,8,1]]}},"alternative-id":["10.1024\/0301-1526.36.3.181"],"URL":"https:\/\/doi.org\/10.1024\/0301-1526.36.3.181","relation":{},"ISSN":["0301-1526","1664-2872"],"issn-type":[{"value":"0301-1526","type":"print"},{"value":"1664-2872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,1]]}}}