{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T17:16:33Z","timestamp":1694625393723},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"41","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2002,10,1]]},"abstract":"<jats:p> Die Sprue oder Z\u00f6liakie ist eine entz\u00fcndliche Erkrankung des D\u00fcnndarmes. Sie tritt bei Individuen mit einer genetisch bedingten Gluten-Unvertr\u00e4glichkeit auf. Malabsorption verschiedener Nahrungsbestandteile und Steatorrhoe k\u00f6nnen die Folge sein. Milde und latente Verl\u00e4ufe werden zunehmend beobachtet. Die Diagnose wird gestellt durch eine Zottenatrophie in der D\u00fcnndarmbiopsie. Serologischer Marker mit hoher Sensitivit\u00e4t und Spezifit\u00e4t ist der Anti-Endomysium-Antik\u00f6rper. Die Erkrankung ist unter einer glutenfreien Ern\u00e4hrung reversibel. Die glutenfreie Di\u00e4t muss lebenslang eingehalten werden, um Komplikationen wie Osteoporose oder Malignome zu vermeiden. <\/jats:p>","DOI":"10.1024\/0369-8394.91.41.1687","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:05:58Z","timestamp":1138709158000},"page":"1687-1690","source":"Crossref","is-referenced-by-count":0,"title":["Sprue"],"prefix":"10.1024","volume":"91","author":[{"family":"Schwacha","sequence":"first","affiliation":[{"name":"Abt. Innere Medizin II, Universit\u00e4tsklinikum Freiburg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0369-8394.91.41.1687","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T11:09:41Z","timestamp":1652008181000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0369-8394.91.41.1687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10,1]]},"references-count":0,"journal-issue":{"issue":"41","published-print":{"date-parts":[[2002,10,1]]}},"alternative-id":["10.1024\/0369-8394.91.41.1687"],"URL":"https:\/\/doi.org\/10.1024\/0369-8394.91.41.1687","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,10,1]]}}}