{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T17:18:19Z","timestamp":1694625499402},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2003,3,1]]},"abstract":"<jats:p> Les verrues r\u00e9calcitrantes peuvent poser un probl\u00e8me th\u00e9rapeutique pour le m\u00e9decin traitant dans la pratique quotidienne. Nous avons \u00e9tudi\u00e9 l'efficacit\u00e9 de la cr\u00e8me Imiquimod (Aldara\u00ae) chez 22 patient(e)s souffrantes de verrues r\u00e9calcitrantes. Une r\u00e9mission compl\u00e8te a pu \u00eatre constat\u00e9e dans 41% et une r\u00e9duction partielle dans 50% des patient(e)s. Dans 9% des cas seulement, Imiquimod ne produisait aucun effet. \u00c0 part un \u00e9ryth\u00e8me peril\u00e9sionnel fr\u00e9quemment observ\u00e9 et \u00e9tant souvent associ\u00e9 \u00e0 une r\u00e9ponse favorable au traitement, il n'y avait pas d'effets secondaires significatifs. Dans le traitement des verrues induites par HPV, Imiquimod cr\u00e8me 5% (Aldara\u00ae) repr\u00e9sente une modalit\u00e9 th\u00e9rapeutique efficace, facile \u00e0 appliquer et bien tol\u00e9r\u00e9e. <\/jats:p>","DOI":"10.1024\/0369-8394.92.12.535","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:07:41Z","timestamp":1138709261000},"page":"535-539","source":"Crossref","is-referenced-by-count":0,"title":["Imiquimod in der Behandlung von therapieresistenten Verrucae \u2013 eine neue Therapieoption?"],"prefix":"10.1024","volume":"92","author":[{"family":"Hesterberg","sequence":"first","affiliation":[{"name":"Dermatologische Universit\u00e4tsklinik, Inselspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"B\u00f6hlen","sequence":"additional","affiliation":[{"name":"Dermatologische Abteilung, Kantonsspital Luzern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Brand","sequence":"additional","affiliation":[{"name":"Dermatologische Abteilung, Kantonsspital Luzern"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0369-8394.92.12.535","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T11:07:30Z","timestamp":1652008050000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0369-8394.92.12.535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,3,1]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2003,3,1]]}},"alternative-id":["10.1024\/0369-8394.92.12.535"],"URL":"https:\/\/doi.org\/10.1024\/0369-8394.92.12.535","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,3,1]]}}}