{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T17:11:34Z","timestamp":1694625094726},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2005,1,1]]},"abstract":"<jats:p> Nous discutons le cas d'une femme de 83 ans qui pr\u00e9sente depuis 2 semaines une asth\u00e9nie, une dyspn\u00e9e progressive, avec apparition d'un ict\u00e8re indolore. Les examens de laboratoire mettent en \u00e9vidence une pancytop\u00e9nie avec une an\u00e9mie h\u00e9molytique s\u00e9v\u00e8re, une thrombop\u00e9nie et une importante schizocytose. Cette association fait \u00e9voquer en premier lieu une microangiopathie thrombotique. L'absence de r\u00e9ticulocytose et de sympt\u00f4mes neurologiques ont permis d'\u00e9carter cette hypoth\u00e8se, alors que la pr\u00e9sence d'une macrocytose \u00e9rythrocytaire et de neutrophiles hypersegment\u00e9s sur le frottis sanguin nous ont orient\u00e9 vers une carence en vitamine B12 et en folates. Apr\u00e8s substitution vitaminique nous avons observ\u00e9 une crise r\u00e9ticulocytaire, puis une normalisation des param\u00e8tres h\u00e9matologiques. <\/jats:p>","DOI":"10.1024\/0369-8394.94.1.31","type":"journal-article","created":{"date-parts":[[2006,1,11]],"date-time":"2006-01-11T15:11:23Z","timestamp":1136992283000},"page":"31-34","source":"Crossref","is-referenced-by-count":0,"title":["Pancytop\u00e9nie, schizocytose et h\u00e9molyse: les pi\u00e8ges diagnostiques d'une pathologie fr\u00e9quente se manifestant comme une pathologie rare et grave"],"prefix":"10.1024","volume":"94","author":[{"family":"Monti","sequence":"first","affiliation":[{"name":"Services de m\u00e9decine, D\u00e9partement de m\u00e9decine, CHUV, Lausanne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Canellini","sequence":"additional","affiliation":[{"name":"Service d'h\u00e9matologie, D\u00e9partement de m\u00e9decine, CHUV, Lausanne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Trueb","sequence":"additional","affiliation":[{"name":"Services de m\u00e9decine, D\u00e9partement de m\u00e9decine, CHUV, Lausanne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Cairoli","sequence":"additional","affiliation":[{"name":"Service d'h\u00e9matologie, D\u00e9partement de m\u00e9decine, CHUV, Lausanne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Lamy","sequence":"additional","affiliation":[{"name":"Services de m\u00e9decine, D\u00e9partement de m\u00e9decine, CHUV, Lausanne"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0369-8394.94.1.31","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:47:27Z","timestamp":1652006847000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0369-8394.94.1.31"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1,1]]}},"alternative-id":["10.1024\/0369-8394.94.1.31"],"URL":"https:\/\/doi.org\/10.1024\/0369-8394.94.1.31","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1,1]]}}}