{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T20:57:19Z","timestamp":1762808239670},"reference-count":102,"publisher":"Hogrefe Publishing Group","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zeitschrift f\u00fcr Kinder- und Jugendpsychiatrie und Psychotherapie"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p> Anorexia nervosa ist eine psychosomatische Erkrankung mit hoher Morbidit\u00e4t und Mortalit\u00e4t, die meist bei M\u00e4dchen und jungen Frauen auftritt. Bisher gibt es keine Hinweise auf die \u00dcberlegenheit eines bestimmten Therapieverfahrens ( Herpertz et al., 2011 ). W\u00e4hrend der klinische Ph\u00e4notyp bislang im Fokus stand, werden immer h\u00e4ufiger Methoden und Ans\u00e4tze verwendet, die in der Anorexieforschung bisher unterrepr\u00e4sentiert waren. Diese beinhalten zum einen die Untersuchung endokrinologischer Merkmale wie z. B. Hormone und andere Mediatoren, die wichtige Vorg\u00e4nge der Gewichts- und Appetitregulation beeinflussen, aber auch die Erforschung von kognitiven Ver\u00e4nderungen und Pers\u00f6nlichkeitsmerkmalen, die oft auch nach Ende der akuten Krankheitsphase noch messbar sind. Dabei ist es vor allem wichtig, pr\u00e4disponierende und die Krankheit aufrechterhaltende Faktoren zu identifizieren und zu unterscheiden. Nicht zuletzt erm\u00f6glichen bildgebende Verfahren seit einigen Jahren die genauere Untersuchung von funktionellen Zusammenh\u00e4ngen verschiedener Gehirnareale, die diesen pr\u00e4disponierenden und aufrechterhaltenden Faktoren zugrunde liegen k\u00f6nnten. 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