{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:26:07Z","timestamp":1787905567080,"version":"build-2784847793"},"reference-count":71,"publisher":"Hogrefe Publishing Group","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zeitschrift f\u00fcr Kinder- und Jugendpsychiatrie und Psychotherapie"],"abstract":"<jats:p> Zusammenfassung: In diesem kurzen \u00dcberblick soll die Literatur zu therapeutischen Interventionen mit Pr\u00e4- und Probiotika f\u00fcr psychiatrische St\u00f6rungen im Kindes-, Jugend- und Erwachsenenalter zusammengefasst und dadurch das Potenzial von Pr\u00e4- und Probiotika f\u00fcr den Einsatz in der Kinder- und Jugendpsychiatrie abgeleitet werden. Im Kindes- und Jugendalter finden sich derzeit vorrangig Studien zur Aufmerksamkeitsdefizit-\/Hyperaktivit\u00e4tsst\u00f6rung und Autismus-Spektrum-St\u00f6rung, welche vereinzelt positive Effekte von Probiotika auf die kognitive Symptomatik und Lebensqualit\u00e4t zeigen. Erste Studien mit Jugendlichen mit Anorexia nervosa weisen auf das Potenzial einer Probiotikagabe als Unterst\u00fctzung f\u00fcr die Gewichtszunahme und zur Verringerung gastrointestinaler Beschwerden hin. Die Wirksamkeit von Pr\u00e4- und Probiotika bei Depression, bipolarer St\u00f6rung, Angstst\u00f6rungen und Schizophrenie wurden bis dato vorrangig bei erwachsenen Patient_innen untersucht. Die h\u00f6chste Evidenz f\u00fcr Pr\u00e4- und Probiotikainterventionen zeigt sich derzeit bei den depressiven St\u00f6rungen, wobei die Effekte auf die depressive Symptomatik meist gering ausfallen. Positive Evidenz zeigt sich auch f\u00fcr gastrointestinale Begleiterscheinungen bei diesen psychiatrischen Erkrankungen. Trotz dieser positiven Effekte weist die vorhandene Literatur allerdings sehr gemischte Effekte auf, die unter anderem aus sehr heterogenen Studiendesigns resultieren k\u00f6nnen. Dennoch zeigt sich ein vielversprechendes Potenzial von Pr\u00e4- und Probiotika f\u00fcr den Kinder- und Jugendbereich. Weitere Studien unter Einbezug kinder- und jugendpsychiatrischer Patient_innen, die die Komplexit\u00e4t der Darm-Hirn-Achse ber\u00fccksichtigen, sind dringend notwendig. <\/jats:p>","DOI":"10.1024\/1422-4917\/a000930","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T09:01:42Z","timestamp":1681808502000},"source":"Crossref","is-referenced-by-count":3,"title":["Zum therapeutischen Potenzial der Gabe von Pr\u00e4biotika und                     Probiotika bei kinder- und jugendpsychiatrischen Erkrankungen"],"prefix":"10.1024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8194-4075","authenticated-orcid":true,"given":"Andrea","family":"Schneider","sequence":"first","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Kinder-                     und Jugendpsychiatrie, Medizinische Universit\u00e4t Wien,                         \u00d6sterreich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7087-6134","authenticated-orcid":true,"given":"Michael","family":"Zeiler","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Kinder-                     und Jugendpsychiatrie, Medizinische Universit\u00e4t Wien,                         \u00d6sterreich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4841-8118","authenticated-orcid":true,"given":"Konstantin","family":"Kopp","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Kinder-                     und Jugendpsychiatrie, Medizinische Universit\u00e4t Wien,                         \u00d6sterreich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4845-9684","authenticated-orcid":true,"given":"Gudrun","family":"Wagner","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Kinder-                     und Jugendpsychiatrie, Medizinische Universit\u00e4t Wien,                         \u00d6sterreich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9053-998X","authenticated-orcid":true,"given":"Andreas","family":"Karwautz","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Kinder-                     und Jugendpsychiatrie, Medizinische Universit\u00e4t Wien,                         \u00d6sterreich"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"101","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2019.10.011"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-018-1732-z"},{"key":"c3","first-page":"486","volume":"9","author":"Bagga D.","year":"2018","journal-title":"Gut Microbes"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1093\/nutrit\/nuz080"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02566-18"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-022-01817-y"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1016\/j.conctc.2022.100960"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.1177\/0706743719874168"},{"key":"c9","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-017-0969-z"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-015-9375-7"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00018.2018"},{"key":"c12","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2022.105959"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12652"},{"key":"c14","volume":"16","author":"Dickerson F. 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