{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:49:53Z","timestamp":1761947393151},"reference-count":42,"publisher":"Hogrefe Publishing Group","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zeitschrift f\u00fcr Kinder- und Jugendpsychiatrie und Psychotherapie"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:p> Zusammenfassung: In fr\u00fchen Bildgebungsstudien zur Untersuchung der neurobiologischen Korrelate des phonologischen Defizits der LRS konnten aufgrund der radioaktiven Belastung im Rahmen von PET-Untersuchungen lediglich erwachsene Probanden mit LRS untersucht werden. Die in diesen Studien beobachteten Aktivierungsunterschiede zwischen normallesenden erwachsenen Probanden und Probanden mit LRS lie\u00dfen die Frage offen, ob es sich hierbei um grundlegende Aktivierungsdefizite handelte oder ob sie als Abbild der lebenslangen Erfahrung mit schlechten Lese- und Rechtschreibf\u00e4higkeiten und somit als Zeichen von Kompensation zu werten waren. Durch den Einsatz des fMRI konnten in den letzten Jahren auch Kinder mit LRS untersucht werden, um die der LRS zugrunde liegenden neurobiologischen Aktivierungsmuster zu untersuchen. Insgesamt deuten die Bildgebungsbefunde bei Kindern und Erwachsenen mit LRS darauf hin, dass die linkshemisph\u00e4rischen inferior frontalen sowie dorsalen und ventralen temporalen Aktivierungsunterschiede, die in allen Altersstufen bei der Verarbeitung von phonologischen Sprachaufgaben zu beobachten sind, als grundlegendes neurobiologisches Defizit der LRS gewertet werden k\u00f6nnen. Rechtshemisph\u00e4rische Aktivierungsunterschiede, die im deutschen Sprachraum zwar bei Erwachsenen, aber nur in sehr geringem Ma\u00dfe bei Kindern mit LRS zu beobachten sind, k\u00f6nnten hingegen als Abbild von entwicklungsbedingten Kompensationsprozessen zu werten sein. <\/jats:p>","DOI":"10.1024\/1422-4917.35.2.107","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T19:38:53Z","timestamp":1173123533000},"page":"107-117","source":"Crossref","is-referenced-by-count":14,"title":["\u00dcbersicht \u00fcber Bildgebungs- befunde zum phonologischen Defizit der Lese-Rechtschreibst\u00f6rung bei Kindern und Erwachsenen: Grundlegende Defizite oder Anzeichen von Kompensation?"],"prefix":"10.1024","volume":"35","author":[{"given":"Carolin","family":"Ligges","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Kinder- und Jugendpsychiatrie und Psychotherapie, Universit\u00e4tsklinikum Jena (\u00c4rztlicher Direktor: Prof. Dr. B. 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