{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T01:33:32Z","timestamp":1774316012750,"version":"3.50.1"},"reference-count":33,"publisher":"Hogrefe Publishing Group","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zeitschrift f\u00fcr Kinder- und Jugendpsychiatrie und Psychotherapie"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:p> Zusammenfassung: Fragestellung: Im deutschen Raum gibt es kaum Familienuntersuchungen von Patienten mit Anorexia und Bulimia nervosa. Methodik: In einer Multizenter Studie wurde das Auftreten psychiatrischer Erkrankungen bei Familienangeh\u00f6rigen 1., 2. und 3. Grades von 65 anorektischen (n = 746) und 21 bulimischen Patienten (n = 265) mit denen von 37 gesunden Kontrollen (n = 480) sowie 11 depressiven Patienten (n = 157) verglichen. Messinstrumente waren u.a. das Diagnostische Interview f\u00fcr Genetische Studien bzw. das Familien Interview f\u00fcr Genetische Studien. Ergebnisse: Die Pr\u00e4valenz von Anorexia nervosa (signifikant) sowie von depressiven St\u00f6rungen (Trend) war bei Verwandten 1. und 2. Grades von Patienten mit Essst\u00f6rungen gegen\u00fcber der gesunden Gruppe erh\u00f6ht. Die meisten Ergebnisse waren eher bei den Familien bulimischer Patienten ausgepr\u00e4gt. Die Pr\u00e4valenzraten f\u00fcr psychiatrische Erkrankungen waren insgesamt prozentual niedriger als in vergleichbaren US amerikanischen Stichproben. Schlussfolgerung: Die Ergebnisse k\u00f6nnten f\u00fcr eine famili\u00e4re Vulnerabilit\u00e4t bzw. genetisches Risiko von Patienten mit Anorexia und Bulimia nervosa sprechen. Der Zusammenhang des niedrigen Alters der Indexpatienten auf die geringeren Pr\u00e4valenzraten wird diskutiert. <\/jats:p>","DOI":"10.1024\/1422-4917.36.3.177","type":"journal-article","created":{"date-parts":[[2008,5,13]],"date-time":"2008-05-13T16:21:16Z","timestamp":1210695676000},"page":"177-184","source":"Crossref","is-referenced-by-count":4,"title":["Psychiatrische Erkrankungen bei Verwandten von Patienten mit Anorexia nervosa und Bulimia nervosa"],"prefix":"10.1024","volume":"36","author":[{"given":"Angela","family":"Wagner","sequence":"first","affiliation":[{"name":"J.W. Goethe- Universit\u00e4t Frankfurt, Klinik f\u00fcr Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Frankfurt,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"W\u00f6ckel","sequence":"additional","affiliation":[{"name":"J.W. 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