{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T21:07:05Z","timestamp":1694639225270},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2010,5,1]]},"abstract":"<jats:p> Differentialdiagnostisch sollte bei Rauchern im jungen Erwachsenenalter mit einem nodul\u00e4ren Oberlappeninfiltrat im Thoraxr\u00f6ntgenbild an die pulmonale Histiozytose X gedacht werden. Fehlender Nikotinabusus und ein Alter \u00fcber 60 Jahren machen die Erkrankung unwahrscheinlich. Die Computertomographie erlaubt aufgrund pathognomonischer L\u00e4sionen h\u00e4ufig eine Diagnose, die jedoch mittels Bronchoskopie und\/oder chirurgischer Lungenbiopsie best\u00e4tigt werden sollte. Ein Nachweis von &gt;5% CD1a-positiver Zellen in der BAL ist diagnostisch. Die Nikotinentw\u00f6hnung ist die wichtigste therapeutische Massnahme. <\/jats:p>","DOI":"10.1024\/1661-8157\/a000146","type":"journal-article","created":{"date-parts":[[2010,5,27]],"date-time":"2010-05-27T02:32:06Z","timestamp":1274927526000},"page":"671-674","source":"Crossref","is-referenced-by-count":0,"title":["Eine seltene diffuse Lungenparenchymerkrankung bei zwei Rauchern"],"prefix":"10.1024","volume":"99","author":[{"family":"Mayer","sequence":"first","affiliation":[{"name":"Departement f\u00fcr Innere Medizin, Kantonsspital Graub\u00fcnden, Chur"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Gadient","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie und Rechtsmedizin, Kantonssital Graub\u00fcnden, Chur"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Kuhn","sequence":"additional","affiliation":[{"name":"Departement f\u00fcr Innere Medizin, Kantonsspital Graub\u00fcnden, Chur"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a000146","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:04:21Z","timestamp":1652004261000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a000146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,1]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010,5,1]]}},"alternative-id":["10.1024\/1661-8157\/a000146"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a000146","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,1]]}}}