{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T06:20:08Z","timestamp":1703226008291},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2010,11,1]]},"abstract":"<jats:p> Das Gilles de la Tourette-Syndrom (GTS) ist eine Erkrankung, deren Hauptmerkmal das Auftreten motorischer und vokaler Tics ist. Ein Tic ist eine unwillk\u00fcrliche, schnelle und pl\u00f6tzliche, stereotype Bewegung oder Laut\u00e4usserung. Die leitliniengerechte Therapie der St\u00f6rung besteht in pharmakologischen, psychotherapeutischen und neurochirurgischen Ans\u00e4tzen. Neuroleptika stellen die derzeit wirksamste Pharmakotherapie dar, psychotherapeutische Ans\u00e4tze spielen eine eher nachgeordnete Rolle. Die tiefe Hirnstimulation kommt experimentell bei therapierefrakt\u00e4ren Verl\u00e4ufen zur Anwendung. <\/jats:p>","DOI":"10.1024\/1661-8157\/a000294","type":"journal-article","created":{"date-parts":[[2010,11,4]],"date-time":"2010-11-04T03:32:34Z","timestamp":1288841554000},"page":"1353-1360","source":"Crossref","is-referenced-by-count":4,"title":["Gilles de la Tourette-Syndrom: Behandlung einer neuropsychiatrischen St\u00f6rung"],"prefix":"10.1024","volume":"99","author":[{"family":"Kawohl","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Soziale Psychiatrie und Allgemeinpsychiatrie Z\u00fcrich West, Psychiatrische Universit\u00e4tsklinik Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a000294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:06:00Z","timestamp":1652004360000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a000294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,1]]},"references-count":0,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2010,11,1]]}},"alternative-id":["10.1024\/1661-8157\/a000294"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a000294","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,1]]}}}