{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:41:30Z","timestamp":1652006490010},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2012,4,1]]},"abstract":"<jats:p> Harnwegsinfektionen z\u00e4hlen zu den h\u00e4ufigsten Infektionen. Die Resistenzraten von Escherichia coli, dem h\u00e4ufigsten Erreger der Zystitis, haben weltweit zugenommen. In einer Pr\u00e4valenzstudie ermittelten wir die lokale Resistenzlage sowie Resistenzentwicklung von E. coli anhand von Urinproben aus drei Laboratorien im Raum Z\u00fcrich. 2010 waren 28% der E. coli resistent gegen\u00fcber Cotrimoxazol, 16% gegen\u00fcber den Chinolonen und 16% gegen\u00fcber Amoxicillin\/Clavulans\u00e4ure. Die Resistenzraten gegen\u00fcber Nitrofurantoin und Fosfomycin waren tief mit 3,6%, resp. 0,7%. Der Anteil an extended spectrum beta-lactamase-bildenden E. coli nahm sprunghaft zu und betrug 2010 4,3%. Gem\u00e4ss den internationalen Therapierichtlinien f\u00fcr die unkomplizierte Zystitis wird aufgrund dieser Resultate von einer Therapie mit Cotrimoxazol und Chinolonen abgeraten. Antibiotika der ersten Wahl sind Fosfomycin und Nitrofurantoin. Eine mikrobiologische Diagnostik des Urins wird empfohlen. <\/jats:p>","DOI":"10.1024\/1661-8157\/a000918","type":"journal-article","created":{"date-parts":[[2013,2,2]],"date-time":"2013-02-02T02:09:18Z","timestamp":1359770958000},"page":"573-579","source":"Crossref","is-referenced-by-count":0,"title":["Antibiotikaresistenzen von E.coli in Urinproben: Pr\u00e4valenzdaten dreier Laboratorien im Raum Z\u00fcrich von 1985 bis 2010"],"prefix":"10.1024","volume":"101","author":[{"family":"Savaria","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Infektionskrankheiten und Spitalhygiene, Universit\u00e4t Z\u00fcrich, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Zbinden","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Medizinische Mikrobiologie (IMM), Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"W\u00fcst","sequence":"additional","affiliation":[{"name":"Labor Unilabs SA, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Burnens","sequence":"additional","affiliation":[{"name":"Medica, Medizinische Laboratorien Dr. F. Kaeppeli AG, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Ledergerber","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Infektionskrankheiten und Spitalhygiene, Universit\u00e4t Z\u00fcrich, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Weber","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Infektionskrankheiten und Spitalhygiene, Universit\u00e4t Z\u00fcrich, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Kovari","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Infektionskrankheiten und Spitalhygiene, Universit\u00e4t Z\u00fcrich, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a000918","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:13:28Z","timestamp":1652004808000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a000918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,1]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012,4,1]]}},"alternative-id":["10.1024\/1661-8157\/a000918"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a000918","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,1]]}}}