{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T22:11:37Z","timestamp":1649196697750},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2013,5,1]]},"abstract":"<jats:p> Wir berichten \u00fcber eine 48-j\u00e4hrige Patientin mit Oberbauchschmerzen mit Status nach zerebraler Isch\u00e4mie bei offenem Foramen ovale und heterozygoter Faktor-V-Leiden-Mutation. In der initialen Abkl\u00e4rung der belastungsabh\u00e4ngigen Bauchschmerzen kommt eine ausgepr\u00e4gte Thrombose im portalven\u00f6sen System mit Zeichen der portalen Hypertension (Aszites und ausgepr\u00e4gte \u00d6sophagusvarizen) zur Darstellung. Sonographisch finden sich jedoch keine Hinweise f\u00fcr eine Leberzirrhose. Letztendlich konnte als Ursache der ausgedehnten Thrombose eine JAK2-Mutation nachgewiesen werden. Eine Prim\u00e4rpr\u00e4vention der ausgepr\u00e4gten \u00d6sophagusvarizen wird abgelehnt. Im Verlauf kommt es dann zur Massenblutung. <\/jats:p>","DOI":"10.1024\/1661-8157\/a001303","type":"journal-article","created":{"date-parts":[[2013,5,22]],"date-time":"2013-05-22T01:08:55Z","timestamp":1369184935000},"page":"681-685","source":"Crossref","is-referenced-by-count":0,"title":["Nicht-zirrhotische portale Hypertonie mit beinahe fatalen Folgen"],"prefix":"10.1024","volume":"102","author":[{"given":"Nele","family":"B\u00f6rner","sequence":"first","affiliation":[{"name":"Departement Innere Medizin, Kantonsspital St. Gallen, Spital Rorschach"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Korte","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Labormedizin St. Gallen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Doenecke","sequence":"additional","affiliation":[{"name":"Departement Innere Medizin, Kantonsspital St. Gallen, Spital Rorschach"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurus","family":"Pfister","sequence":"additional","affiliation":[{"name":"Departement Innere Medizin, Kantonsspital St. Gallen, Spital Rorschach"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christa","family":"Meyenberger","sequence":"additional","affiliation":[{"name":"Abteilung Gastroenterologie\/Hepatologie, Kantonsspital St. Gallen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Semela","sequence":"additional","affiliation":[{"name":"Abteilung Gastroenterologie\/Hepatologie, Kantonsspital St. Gallen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikael","family":"Sawatzki","sequence":"additional","affiliation":[{"name":"Abteilung Gastroenterologie\/Hepatologie, Kantonsspital St. Gallen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a001303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T03:32:36Z","timestamp":1615951956000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a001303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,1]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,5,1]]}},"alternative-id":["10.1024\/1661-8157\/a001303"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a001303","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,1]]}}}