{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:32:00Z","timestamp":1761129120955},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2013,10,1]]},"abstract":"<jats:p> Wir berichten \u00fcber einen 52-j\u00e4hrigen Schweizer mit Halsschmerzen und progredienter Heiserkeit. Histologisch fand sich eine granulomat\u00f6se Entz\u00fcndung der Epiglottis. Mikrobiologisch erfolgte der Nachweis von dimorphen Pilzen im Sputum, die als Histoplasma sp. identifiziert wurden. Das Histoplasma-Antigen war positiv im Urin und Serum. Unter der Therapie mit Itroconazol zeigte sich eine weitere Verschlechterung der Klinik, weshalb die antimykotische Therapie auf Amphotericin B umgestellt wurde. An die Nebenniereninsuffizienz muss gedacht werden, da diese durch die Histoplasmose per se aber auch durch die Itraconazol-Therapie verursacht werden kann. Als alternative Therapie der disseminierten Histoplasmose kommt eine Therapie mit Voriconazol infrage. Die Erhebung einer Reiseanamnese ist wichtig. <\/jats:p>","DOI":"10.1024\/1661-8157\/a001469","type":"journal-article","created":{"date-parts":[[2013,10,30]],"date-time":"2013-10-30T02:42:39Z","timestamp":1383100959000},"page":"1377-1381","source":"Crossref","is-referenced-by-count":1,"title":["Heiserkeit nach USA-Reise"],"prefix":"10.1024","volume":"102","author":[{"given":"Aleksandra","family":"Nobile","sequence":"first","affiliation":[{"name":"Innere Medizin, Ospedale Regionale di Lugano, Civico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reto A.","family":"Sch\u00fcpbach","sequence":"additional","affiliation":[{"name":"Intensivstation, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Flepp","sequence":"additional","affiliation":[{"name":"Klinik im Park, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Maggiorini","sequence":"additional","affiliation":[{"name":"Intensivstation, Universit\u00e4tsspital Z\u00fcrich, Universit\u00e4t Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huldrych","family":"G\u00fcnthard","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Infektiologie und Spitalhygiene, Universit\u00e4t Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annelies S.","family":"Zinkernagel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Infektiologie und Spitalhygiene, Universit\u00e4t Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a001469","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T05:36:34Z","timestamp":1615959394000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a001469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,1]]},"references-count":0,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2013,10,1]]}},"alternative-id":["10.1024\/1661-8157\/a001469"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a001469","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,1]]}}}