{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T18:23:57Z","timestamp":1649096637471},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:p> Zusammenfassung. Der PFO-Verschluss nach Schlaganfall zeigte sich in Subanalysen der grossen randomisierten Studien der medikament\u00f6sen Therapie \u00fcberlegen. Dies wurde auch durch mehrere Meta-Analysen best\u00e4tigt. Aufgrund vorliegender Evidenz sollte deshalb das PFO zur Sekund\u00e4rprophylaxe verschlossen werden. Ob das PFO ausserhalb dieser Indikation gesucht und verschlossen werden soll (z.B. bei Migr\u00e4ne-Patienten), ist umstritten und muss unter Erw\u00e4hnung aller Vorteile (z.B. m\u00f6gliche Symptomverbesserung der Migr\u00e4ne, Schutz vor paradoxen Embolien) und Nachteile (bleibendes Implantat) mit dem Patienten besprochen werden. <\/jats:p>","DOI":"10.1024\/1661-8157\/a002243","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T15:16:37Z","timestamp":1453302997000},"page":"93-97","source":"Crossref","is-referenced-by-count":0,"title":["Das offene Foramen ovale \u2013 der\u00a0Blindg\u00e4nger im K\u00f6rper"],"prefix":"10.1024","volume":"105","author":[{"given":"Fabian","family":"Nietlispach","sequence":"first","affiliation":[{"name":"Strukturelle Interventionelle Kardiologie, Universit\u00e4res Herzzentrum, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a002243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T10:12:44Z","timestamp":1615975964000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a002243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1024\/1661-8157\/a002243"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a002243","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1]]}}}