{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T21:45:50Z","timestamp":1649022350673},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p> Zusammenfassung. Unter Z\u00f6liakie versteht man eine immunvermittelte und durch Gluteneinnahme getriggerte Enteropathie bei genetisch pr\u00e4disponierten Individuen. Klinisch kann sich die Z\u00f6liakie sehr mannigfaltig mit intestinalen sowie extraintestinalen Symptomen manifestieren. Daneben gibt es jedoch auch zunehmend asymptomatische Betroffene, bei welchen die Diagnosestellung aufgrund m\u00f6glicher Langzeitkomplikationen genauso essenziell ist. Die Diagnostik besteht in der Bestimmung der Gewebs-Transglutaminase-Antik\u00f6rper mit anschliessender Diagnoseverifizierung mittels Duodenalbiopsie. Auch heute noch besteht die einzige Therapieoption in einer strikten glutenfreien Di\u00e4t. Neuere Therapieans\u00e4tze sind aktuell in Erprobung. <\/jats:p>","DOI":"10.1024\/1661-8157\/a002413","type":"journal-article","created":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T08:59:01Z","timestamp":1467795541000},"page":"803-810","source":"Crossref","is-referenced-by-count":1,"title":["Z\u00f6liakie beim Erwachsenen"],"prefix":"10.1024","volume":"105","author":[{"given":"Natalie","family":"Many","sequence":"first","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Innere Medizin, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Biedermann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Gastroenterologie und Hepatologie, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a002413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T22:25:12Z","timestamp":1615933512000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a002413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":0,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1024\/1661-8157\/a002413"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a002413","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7]]}}}