{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T16:06:46Z","timestamp":1649002006626},"reference-count":5,"publisher":"Hogrefe Publishing Group","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:p> Zusammenfassung. Das akute Koronarsyndrom bleibt weltweit eine f\u00fchrende Ursache f\u00fcr Morbidit\u00e4t und Mortalit\u00e4t. Deshalb sind die rasche Diagnosestellung und die Wahl des Therapieansatzes von entscheidender Bedeutung. Das optimale Timing f\u00fcr Intervention und Revaskularisation h\u00e4ngt von der initialen Risikostratifikation ab. Patienten mit h\u00e4modynamischer Instabilit\u00e4t oder kardiogenem Schock, lebensbedrohlichen Arrhythmien, refrakt\u00e4rer Angina pectoris oder schwerer Herzinsuffizienz sollten unabh\u00e4ngig von EKG-Ver\u00e4nderungen oder kardialen Biomarkern einer sofortigen Koronarangiografie zugef\u00fchrt werden. Patienten mit NSTEMI oder instabiler Angina pectoris mit entsprechend hohem Risikoprofil profitieren von einer fr\u00fchinvasiven Abkl\u00e4rung innerhalb von 24 h. Ein fr\u00fchinvasiver Therapieansatz bei Patienten mit NSTEMI ist sicher und mit einer geringeren Anzahl refrakt\u00e4rer Isch\u00e4mien und einem k\u00fcrzeren Spitalaufenthalt assoziiert. Weniger klar ist die Situation bei asymptomatischen und stabilen Patienten mit NSTEMI, bei denen eine Latenz bis maximal 72 h vertretbar ist. <\/jats:p>","DOI":"10.1024\/1661-8157\/a002787","type":"journal-article","created":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T08:55:42Z","timestamp":1510736142000},"page":"1263-1270","source":"Crossref","is-referenced-by-count":0,"title":["CME"],"prefix":"10.1024","volume":"106","author":[{"given":"Nina","family":"Rosset","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, Stadtspital                Triemli Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars C.","family":"Huber","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, Stadtspital                Triemli Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz","family":"Eberli","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kardiologie, Stadtspital                Triemli Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1606915"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30677-8"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31276-4"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)07349-3"},{"key":"c5","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/eurheartj\/ehv320","volume":"37","author":"Roffi M","year":"2016","journal-title":"Eur Heart J"}],"container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a002787","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T23:04:30Z","timestamp":1615935870000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a002787"}},"subtitle":["Nicht-ST-Hebungsinfarkt (NSTEMI): Definition, Risikostratifikation und                Behandlung Non-ST-Elevation Myocardial Infarction (NSTEMI): Definition, Risk                Stratification and Management"],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":5,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1024\/1661-8157\/a002787"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a002787","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11]]}}}