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Der Provokationstest mit Aspirin bleibt der Gold-Standard f\u00fcr die Diagnose, sollte aber wegen des Risikos eines schweren Asthmaanfalls nur durch den Spezialisten durchgef\u00fchrt werden. Die Grundbehandlung beruht auf der Kombination topischer Kortikosteroide und Montelukast, sowie der Vermeidung von Hemmern der Zyklooxygenase-1. Therapierefrakt\u00e4re F\u00e4lle k\u00f6nnen auf eine Desensibilisierung mit Aspirin oder neuerdings auf Biologika wie Mepolizumab ansprechen.<\/jats:p>","DOI":"10.1024\/1661-8157\/a002830","type":"journal-article","created":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T08:30:04Z","timestamp":1509525004000},"page":"1243-1249","source":"Crossref","is-referenced-by-count":1,"title":["Le syndrome de Widal en pratique clinique"],"prefix":"10.1024","volume":"106","author":[{"given":"Am\u00e9lie","family":"Borgeat Kaeser","sequence":"first","affiliation":[{"name":"Service d\u2019Immunologie et d\u2019Allergie, Centre Hospitalier Universitaire Vaudois, Lausanne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camillo","family":"Ribi","sequence":"additional","affiliation":[{"name":"Service d\u2019Immunologie et d\u2019Allergie, Centre Hospitalier Universitaire Vaudois, Lausanne"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","unstructured":"Widal F, Abrami P, Lermoyez J. 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