{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T18:42:38Z","timestamp":1698777758983},"reference-count":30,"publisher":"Hogrefe Publishing Group","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:p> Zusammenfassung. Immunmodulierende und immunsuppressive Therapien werden immer h\u00e4ufiger eingesetzt. Je nach Wirkungsmechanismus und Grunderkrankung besteht unter diesen Therapien ein erh\u00f6htes Infektionsrisiko. Im klinischen Alltag ist das individuelle Infektionsrisiko abh\u00e4ngig von einer Vielzahl von Patienten-, Umwelt- und Erreger-spezifischen Faktoren. \u00c4ltere und multimorbide Patienten unterliegen einem besonderen Infektionsrisiko. Klassische bakterielle Infektionen mit eventuell atypischer Manifestation, Hepatitis-B-Virus, Herpesviren, Mykobakterien und andere granulomat\u00f6se Infektionen stehen im Vordergrund. Typische klinische Infektionszeichen k\u00f6nnen fehlen und laborchemische Parameter k\u00f6nnen als diagnostisches Tool versagen. Ein systematisches Screening auf latente oder chronische Infektionen vor Einleitung und eine engmaschige Betreuung der Patienten w\u00e4hrend einer immunmodulierenden oder immunsuppressiven Therapie sind n\u00f6tig, um Morbidit\u00e4t und Mortalit\u00e4t zu senken. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003003","type":"journal-article","created":{"date-parts":[[2018,6,20]],"date-time":"2018-06-20T07:46:30Z","timestamp":1529480790000},"page":"689-698","source":"Crossref","is-referenced-by-count":1,"title":["Infektionen unter Immunsuppression"],"prefix":"10.1024","volume":"107","author":[{"given":"Carsten","family":"Depmeier","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Infektionskrankheiten und                Spitalhygiene, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huldrych F.","family":"G\u00fcnthard","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Infektionskrankheiten und                Spitalhygiene, Universit\u00e4tsspital Z\u00fcrich"},{"name":"Institut f\u00fcr Medizinische Virologie,                Universit\u00e4t Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urs C.","family":"Steiner","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Immunologie,                Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4933-1-1"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.01.029"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1002\/art.34530"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1086\/529197"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1007\/s00108-017-0358-1"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61704-9"},{"key":"c7","unstructured":"European Centre for Disease Prevention                   and Control: TECHNICAL REPORT Migrant health: Background                   note to the \u2018ECDC Report on migration and infectious diseases in the                   EU\u2019. 2009. https:\/\/ecdc.europa.eu\/sites\/portal\/files\/media\/en\/publica                   tions\/Publications\/0907_TER_Migrant_health_Background_note.pdf; 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