{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T04:35:36Z","timestamp":1712032536499},"reference-count":7,"publisher":"Hogrefe Publishing Group","issue":"17-18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:p> Zusammenfassung. Ph\u00e4ochromozytome sind seltene Tumoren, die sich vor allem klinisch durch ihre Hormonaktivit\u00e4t mit exzessiver Freisetzung von Katecholaminen manifestieren und aufgrund ihrer vielgestaltigen Klinik oft verz\u00f6gert diagnostiziert werden. Die Diagnostik erfolgt prim\u00e4r biochemisch mit Bestimmung der freien Metanephrine im Plasma bzw. der fraktionierten Metanephrine im 24-h-Urin. Bei der Interpretation sind Kenntnisse bez\u00fcglich der Messmethode und m\u00f6glichen \u00abSt\u00f6rfaktoren\u00bb zentral. Eine Bildgebung erfolgt erst nach biochemischer Sicherung des Katecholaminexzesses. Die chirurgische Exzision ist in den meisten F\u00e4llen kurativ. Lebenslange j\u00e4hrliche biochemische Nachkontrollen werden empfohlen mit Zusatzuntersuchungen bei heredit\u00e4ren F\u00e4llen. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003047","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T07:02:17Z","timestamp":1534921337000},"page":"977-984","source":"Crossref","is-referenced-by-count":1,"title":["CME: Ph\u00e4ochromozytom in der Hausarztpraxis"],"prefix":"10.1024","volume":"107","author":[{"given":"Zoran","family":"Erlic","sequence":"first","affiliation":[{"name":"Abteilung f\u00fcr                Endokrinologie\/Diabetologie, Luzerner Kantonsspital"},{"name":"Klinik f\u00fcr Endokrinologie, Diabetologie                und klinische Ern\u00e4hrung, Universit\u00e4tsspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Fischli","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr                Endokrinologie\/Diabetologie, Luzerner Kantonsspital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-1498"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0496"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2011.10.008"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1128139"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0303"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.11.1427"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-017-1300-y"}],"container-title":["Praxis"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a003047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T07:45:52Z","timestamp":1615967152000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a003047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":7,"journal-issue":{"issue":"17-18","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1024\/1661-8157\/a003047"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a003047","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8]]}}}