{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T18:12:57Z","timestamp":1772561577446,"version":"3.50.1"},"reference-count":65,"publisher":"Hogrefe Publishing Group","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2019,6]]},"abstract":" Zusammenfassung. Zusammenfassung: Die ketogene Di\u00e4t (KD) ist eine sehr fettreiche und stark kohlenhydratreduzierte Ern\u00e4hrungsform, die bisher vor allem bei Kindern mit therapierefrakt\u00e4rer Epilepsie eingesetzt wird. Die Anwendung der KD bei anderen Krankheitsbildern wird zunehmend diskutiert. Diese \u00dcbersicht zeigt, dass erste Hinweise f\u00fcr einen klinischen Nutzen der KD beim Diabetes mellitus Typ 2 (T2DM) und beim Polyzystischen Ovarialsyndrom (PCOS) bestehen. In vielen analysierten Studien f\u00fchrte die KD zu einem signifikanten Gewichtsverlust und hatte eine g\u00fcnstige Wirkung auf das Lipoproteinprofil und die Insulinresistenz. Der HbA1c-Wert nahm durch die KD bei der H\u00e4lfte der kontrollierten T2DM-Studien signifikant st\u00e4rker ab (HbA1c-Differenz: \u20130,5 bis \u20131,5 %) als durch Vergleichsdi\u00e4ten (HbA1c-Differenz: +0,2 bis \u20130,5 %). Insgesamt sind die Studienresultate jedoch f\u00fcr eine allgemeine Empfehlung der KD bei diesem Patientenkollektiv zu heterogen. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003246","type":"journal-article","created":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T06:00:23Z","timestamp":1560319223000},"page":"541-553","source":"Crossref","is-referenced-by-count":8,"title":["Ketogene Di\u00e4t: evidenzbasierte therapeutische Anwendung bei endokrinologischen Erkrankungen"],"prefix":"10.1024","volume":"108","author":[{"given":"Rahel Kristina","family":"Stocker","sequence":"first","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Diabetologie, Endokrinologie, Ern\u00e4hrungsmedizin & Metabolismus (UDEM), Inselspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilie","family":"Reber Aubry","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Diabetologie, Endokrinologie, Ern\u00e4hrungsmedizin & Metabolismus (UDEM), Inselspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilly","family":"Bally","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Diabetologie, Endokrinologie, Ern\u00e4hrungsmedizin & Metabolismus (UDEM), Inselspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Marc","family":"Nuoffer","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Labormedizin, Inselspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeno","family":"Stanga","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Diabetologie, Endokrinologie, Ern\u00e4hrungsmedizin & Metabolismus (UDEM), Inselspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"crossref","unstructured":"Sumithran P & Proietto J: Ketogenic diets for weight loss: A review of their principles, safety and efficacy. 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