{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T23:12:18Z","timestamp":1648854738183},"reference-count":9,"publisher":"Hogrefe Publishing Group","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p> Zusammenfassung. Die Leptospirose ist eine weltweit h\u00e4ufige Zoonose, die auch in der Schweiz vorkommt. H\u00e4ufig zeigt sich eine selbstlimitierende, milde Erkrankungsform. Bei einem schweren Verlauf mit Ikterus und schwerer akuter Nierensch\u00e4digung (Morbus Weil) besteht jedoch eine hohe Morbidit\u00e4t und Mortalit\u00e4t. Um die Diagnose zu stellen, ist es wichtig, die typischen Befunde zu erkennen und die entsprechende Diagnostik durchzuf\u00fchren. Wir diskutieren in diesem Artikel die Klinik, Diagnostik, Therapie und Pr\u00e4vention der Leptospirose und pr\u00e4sentieren den Fall eines 54-j\u00e4hrigen Patienten mit schwerer Leptospirose. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003255","type":"journal-article","created":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T06:00:23Z","timestamp":1560319223000},"page":"519-524","source":"Crossref","is-referenced-by-count":1,"title":["CME: Zoonosen in der Schweiz: Leptospirose CME-Fragen"],"prefix":"10.1024","volume":"108","author":[{"given":"Isabelle","family":"Vock","sequence":"first","affiliation":[{"name":"Medizinische Klinik, Spital Rheinfelden, Gesundheitszentrum Fricktal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marleen Carina","family":"Scholz","sequence":"additional","affiliation":[{"name":"Intensivmedizin, Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph David","family":"Stettler","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Transplantationsimmunologie und Nephrologie, Universit\u00e4tsspital                Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duncan Wolfe","family":"Shabb","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aur\u00e9lien Emmanuel","family":"Martinez","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Infektiologie und Spitalhygiene, Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"crossref","unstructured":"Lane A &                Dore M:                Leptospirosis: A clinical review of evidence based diagnosis,                   treatment and prevention. World J Clin Infect                      Dis 2016; 6:                61\u201366.","DOI":"10.5495\/wjcid.v6.i4.61"},{"key":"c2","doi-asserted-by":"crossref","unstructured":"Costa F &                Hagan J et al.: Global morbidity and mortality of leptospirosis:                   a systematic review. PLoS Negl Trop                      Dis 2015; 9: e0003898.","DOI":"10.1371\/journal.pntd.0003898"},{"key":"c3","doi-asserted-by":"crossref","unstructured":"Schreiber P,                Aceto L,                Korach R,                Marreros N,                Ryser-Degiorgis MP &                G\u00fcnthard HF:                Cluster of leptospirosis acquired through river surfing in                   Switzerland. Open Forum Infect Dis 2015, 2: ofv102.","DOI":"10.1093\/ofid\/ofv102"},{"key":"c4","unstructured":"WHO: Human leptospirosis:                guidance for diagnosis, surveillance, and control.                Switzerland: World Health                   Organization, Geneva: 2003."},{"key":"c5","doi-asserted-by":"crossref","unstructured":"Bharti A &                Nally J et al.: Leptospirosis: a zoonotic disease of global                   importance. Lancet Infect Dis 2003; 3:                757\u2013771.","DOI":"10.1016\/S1473-3099(03)00830-2"},{"key":"c6","unstructured":"Centers for Disease Control and                Prevention. Leptospirosis (Leptospira interrogans) 2013                   Case Definition. 2013; https:\/\/www.cdc.gov\/nndss\/conditions\/leptospirosis\/case-definition\/2013\/;                letzter Zugriff: 08.02.2019."},{"key":"c7","unstructured":"Faine S:                World Health Organization. Guidelines for the control of                   leptospirosis. World Health                      Organization, Geneva:                1982."},{"key":"c8","doi-asserted-by":"crossref","unstructured":"Brett-Major D &                Coldren R:                Antibiotics for leptospirosis.                Cochrane Database Syst Rev 2012; CD008264.","DOI":"10.1002\/14651858.CD008264.pub2"},{"key":"c9","doi-asserted-by":"crossref","unstructured":"Guerrier G,                Lefevre P,                Chouvin C &                D\u2019Ortenzio E:                Jarisch-Herxheimer reaction among patients with leptospirosis:                   incidence and risk factors. Am J Trop Med                      Hyg 2017; 96:                791\u2013794.","DOI":"10.4269\/ajtmh.16-0457"}],"container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a003255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:13:44Z","timestamp":1615940024000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a003255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1024\/1661-8157\/a003255"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a003255","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}