{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T12:37:20Z","timestamp":1648643840289},"reference-count":14,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p> Zusammenfassung. Nebenschilddr\u00fcsenkarzinome sind seltene endokrine Tumoren. Die klinischen, biochemischen und radiologischen Befunde \u00fcberschneiden sich weitgehend mit denen eines prim\u00e4ren Hyperparathyreoidismus. Entsprechend ist eine pr\u00e4operative Diagnosestellung herausfordernd. Wir schildern den Fall eines 67-j\u00e4hrigen Patienten mit unerwarteter Diagnose eines Nebenschilddr\u00fcsenkarzinoms bei der operativen Therapie eines prim\u00e4ren Hyperparathyreoidismus. Spezifische Kriterien f\u00fcr die pr\u00e4operative Diagnose von Nebenschilddr\u00fcsenkarzinomen existieren derzeit nicht. Die Entstehung von Nebenschilddr\u00fcsenkarzinomen ist h\u00e4ufig auf die Mutation eines Tumorsuppressorgens zur\u00fcckzuf\u00fchren. Die Kenntnis des Mutationsstatus und der Familienanamnese ist somit wesentlich. Die erfolgreiche Therapie h\u00e4ngt prim\u00e4r von der vollst\u00e4ndigen chirurgischen Resektion des malignen Nebenschilddr\u00fcsengewebes ab. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003388","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T19:45:52Z","timestamp":1588103152000},"page":"291-296","source":"Crossref","is-referenced-by-count":0,"title":["Unerwartete postoperative Diagnose eines                     Nebenschilddr\u00fcsenkarzinoms"],"prefix":"10.1024","volume":"109","author":[{"given":"Martin","family":"Litzel","sequence":"first","affiliation":[{"name":"Abteilung Endokrinologie, Diabetologie und klinische Ern\u00e4hrung,                     Luzerner Kantonsspital Luzern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Henzen","sequence":"additional","affiliation":[{"name":"Abteilung Endokrinologie, Diabetologie und klinische Ern\u00e4hrung,                     Luzerner Kantonsspital Luzern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lana","family":"Fourie","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Allgemein- und Viszeralchirurgie, Luzerner                     Kantonsspital Luzern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Fischli","sequence":"additional","affiliation":[{"name":"Abteilung Endokrinologie, Diabetologie und klinische Ern\u00e4hrung,                     Luzerner Kantonsspital Luzern"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","volume":"4","author":"Lloyd RV","year":"2017","journal-title":"WHO classification of tumours of endocrine organs"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-015-1361-4"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-009-0115-4"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1714213"},{"key":"c5","first-page":"234","volume":"4","author":"Kandil E","year":"2011","journal-title":"Int J Clin Exp Med"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-1571"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12523"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031237"},{"key":"c9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2014.10.007"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.2.7207"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-010-0042-6"},{"key":"c12","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2018.09.009"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-015-3130-6"},{"key":"c14","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2018.06.013"}],"container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a003388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T07:07:35Z","timestamp":1615964855000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a003388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1024\/1661-8157\/a003388"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a003388","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3]]}}}