{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T04:17:55Z","timestamp":1681532275449},"reference-count":8,"publisher":"Hogrefe Publishing Group","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:p> Zusammenfassung. Eine paraneoplastische ACTH-Produktion tritt bei diversen Tumorentit\u00e4ten auf, vor allem aber bei kleinzelligen Bronchialkarzinomen. Die Patienten pr\u00e4sentieren sich mit einem sekund\u00e4ren Cushing-Syndrom mit Hypokali\u00e4mie, arterieller Hypertonie, Hyperglyk\u00e4mie und \u00d6demen. Folgende drei Therapies\u00e4ulen bestehen: Eine Behandlung der Grunderkrankung, eine medikament\u00f6se antihormonelle und eine symptomatische Therapie. Die Prognose eines ACTH-produzierenden Bronchialkarzinoms ist aufgrund der hohen Komplikationsrate insgesamt infaust. In unserem Fall lehnte die Patientin die Behandlung der Grunderkrankung ab, weshalb die palliative Behandlung mit symptomatischer Therapie in den Vordergrund r\u00fcckte. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003433","type":"journal-article","created":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T03:30:20Z","timestamp":1590550220000},"page":"517-519","source":"Crossref","is-referenced-by-count":0,"title":["Oft nur Nebenschauplatz, manchmal aber wegweisend \u2013 eine                     ektope ACTH-Sekretion als Beispiel eines paraneoplastischen                     Syndroms"],"prefix":"10.1024","volume":"109","author":[{"given":"Christoph","family":"Herda","sequence":"first","affiliation":[{"name":"Innere Medizin, Kantonsspital                     Graub\u00fcnden, Chur"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sina-Maria","family":"Steck","sequence":"additional","affiliation":[{"name":"Innere Medizin, Kantonsspital                     Graub\u00fcnden, Chur"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Fehr","sequence":"additional","affiliation":[{"name":"Innere Medizin, Kantonsspital                     Graub\u00fcnden, Chur"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristian","family":"Camartin","sequence":"additional","affiliation":[{"name":"Innere Medizin, Kantonsspital                     Graub\u00fcnden, Chur"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.42.831"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1992.10.1.21"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-010368"},{"key":"c4","volume":"2018","author":"Lobo Ferreira T","year":"2018","journal-title":"BMJ Case Rep"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-010-9139-z"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.04.2010.2917"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27302007000800007"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-227068"}],"container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a003433","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T11:03:08Z","timestamp":1681470188000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a003433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1024\/1661-8157\/a003433"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a003433","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5]]}}}