{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T23:04:00Z","timestamp":1648854240747},"reference-count":24,"publisher":"Hogrefe Publishing Group","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2020,10]]},"abstract":" Zusammenfassung. Die Masern sind eine hoch ansteckende, akute und febrile Krankheit, die durch eine Infektion mit dem Masernvirus verursacht wird. Gem\u00e4ss Sch\u00e4tzungen der Weltgesundheitsorganisation (WHO) kommt es bei einer weltweiten Pr\u00e4valenz von zehn Millionen Patientinnen und Patienten pro Jahr zu rund 142 000 Todesf\u00e4llen (Mortalit\u00e4tsrate 1,4 %). Klinisch zeigt sich ein stadienhafter Verlauf: Drei bis vier Tage nach dem initialen katarrhalischen Prodromalstadium mit Fieber und Krankheitsgef\u00fchl bildet sich das charakteristische Exanthem aus. Die Diagnosestellung erfolgt prim\u00e4r klinisch, muss aber laborchemisch durch den Nachweis von spezifischen IgM-Antik\u00f6rpern im Serum oder Virus-RNA im Rachenabstrich best\u00e4tigt werden. Die Therapie ist rein supportiv, eine spezifische antivirale Behandlung existiert nicht. Der Pr\u00e4vention kommt daher ein absolut zentraler Stellenwert zu, da es sich bei den Masern um eine durch Impfstoffe vermeidbare Erkrankung handelt. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003587","type":"journal-article","created":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T03:00:26Z","timestamp":1603854026000},"page":"1109-1116","source":"Crossref","is-referenced-by-count":0,"title":["CME-Dermatologie 22: Masern \u2013 Epidemiologie und Klinik"],"prefix":"10.1024","volume":"109","author":[{"given":"Luc","family":"Hari","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Dermatologie und Venerologie, Departement f\u00fcr Innere Medizin, Stadtspital Triemli, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Lautenschlager","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Dermatologie und Venerologie, Departement f\u00fcr Innere Medizin, Stadtspital Triemli, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","unstructured":"Bennett JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett\u2019s Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA; Elsevier\/Saunders: 2019. 2110\u20132116."},{"key":"c2","doi-asserted-by":"crossref","unstructured":"Moss WJ, Griffin DE. Measles. Lancet. 2012;379:153\u2013164.","DOI":"10.1016\/S0140-6736(10)62352-5"},{"key":"c3","doi-asserted-by":"crossref","unstructured":"Moss WJ. Measles. Lancet. 2017;390:2490\u20132502.","DOI":"10.1016\/S0140-6736(17)31463-0"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2016.01.019"},{"key":"c5","unstructured":"WHO \u2013 World Health Organization. More than 140,000 die from measles as cases surge worldwide: 2019 [Internet]. https:\/\/www.who.int\/news-room\/detail\/05-12-2019-more-than-140-000-die-from-measles-as-cases-surge-worldwide; letzter Zugriff: 17.08.2020."},{"key":"c6","unstructured":"Bundesamt f\u00fcr Gesundheit BAG. 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