{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T21:02:36Z","timestamp":1648760556875},"reference-count":15,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p> Zusammenfassung. Eisenmangel ist h\u00e4ufig und beeinflusst den Verlauf vieler chronischer Erkrankungen. Die Diagnose einer absoluten und manifesten Eisenmangelan\u00e4mie kann leicht durch Messung der H\u00e4moglobin- und Serumferritinspiegel gestellt werden. Bei entz\u00fcndlichen Erkrankungen kann die Diagnose durch zus\u00e4tzliche Laborparameter wie dem l\u00f6slichen Transferrin-Rezeptor erleichtert werden. Bei mehreren chronischen Erkrankungen wie Herz- oder Niereninsuffizienz gelten je nach Krankheit und Stadium unterschiedliche und h\u00f6here Schwellenwerte f\u00fcr Serumferritin, manchmal auch unter zus\u00e4tzlicher Ber\u00fccksichtigung der Transferrins\u00e4ttigung. Die Transferrins\u00e4ttigung ist zudem wichtig f\u00fcr die Diagnostik der H\u00e4mochromatose. Bei Patientinnen und Patienten mit Transferrins\u00e4ttigung &gt;45 % erfordert die Diagnose in der Regel den Nachweis der Homozygotie f\u00fcr die C282Y-Mutation im HFE-Gen. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003637","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T10:46:37Z","timestamp":1615977997000},"page":"181-186","source":"Crossref","is-referenced-by-count":0,"title":["CME-Labor 63: Eisenstoffwechsel-Diagnostik"],"prefix":"10.1024","volume":"110","author":[{"given":"Arnold","family":"von Eckardstein","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Klinische Chemie, Universit\u00e4tsspital                     Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-05-815944"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13004"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000315"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2018.07.015"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2020.1824898"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2020.1787326"},{"key":"c7","volume":"149","author":"Nowak A","year":"2019","journal-title":"Swiss Medical Weekly"},{"key":"c8","unstructured":"Breymann C,                                 Honegger C,                                 H\u00f6sli I.                         Diagnostik und Therapie der Eisenmangelan\u00e4mie in der                         Schwangerschaft und postpartal.                             Expertenbrief Nr. 48 (ersetzt Nr. 22),                         SGGG 11.1.2017. 2017."},{"key":"c9","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/ejhf.592","volume":"18","author":"Ponikowski P","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jju009"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gft033"},{"key":"c12","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/kisup.2012.37","volume":"2","author":"KDIGO","year":"2012","journal-title":"Kidney Int Suppl"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1111\/anae.13773"},{"key":"c14","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx758"},{"key":"c15","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2017.11.1126"}],"container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a003637","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T10:49:35Z","timestamp":1615978175000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a003637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1024\/1661-8157\/a003637"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a003637","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}