{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T16:07:43Z","timestamp":1689264463872},"reference-count":45,"publisher":"Hogrefe Publishing Group","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p> Zusammenfassung. Hidradenitis suppurativa (Acne inversa) ist eine chronische Hauterkrankung, die durch wiederkehrende entz\u00fcndliche Kn\u00f6tchen, Abszesse und Narben in den intertrigin\u00f6sen Bereichen gekennzeichnet ist. Die Pr\u00e4valenz der Erkrankung wird weltweit auf 0,05 bis 4,1 % gesch\u00e4tzt, wobei Frauen h\u00e4ufiger betroffen sind. Die genaue Pathogenese bleibt unklar, aber der Verschluss und die Entz\u00fcndung der Haarfollikel scheinen die ausl\u00f6senden Ereignisse zu sein. Es wurden verschiedene epidemiologische Korrelationen mit Rauchen und Fettleibigkeit sowie Mutationen in Gamma-Sekretase-Genen beschrieben. Die Therapie h\u00e4ngt von der Ausdehnung der Krankheit ab und sollte die aktuellen Richtlinien einhalten. Topisches Clindamycin ist f\u00fcr milde Formen der Krankheit geeignet, w\u00e4hrend mittelschwere bis schwere Krankheiten eine systemische entz\u00fcndungshemmende Behandlung erfordern. Ein chirurgischer Eingriff ist derzeit die einzige endg\u00fcltige Behandlung f\u00fcr Hidradenitis suppurativa. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003693","type":"journal-article","created":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T17:31:50Z","timestamp":1621618310000},"page":"363-372","source":"Crossref","is-referenced-by-count":1,"title":["CME-Dermatologie 23: Hidradenitis suppurativa"],"prefix":"10.1024","volume":"110","author":[{"given":"Robert A.","family":"Dahmen","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Dermatologie und Venerologie, Stadtspital Waid und                Triemli, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Lautenschlager","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Dermatologie und Venerologie, Stadtspital Waid und                Triemli, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","doi-asserted-by":"publisher","DOI":"10.1159\/000453355"},{"key":"c2","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15233"},{"key":"c3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.07.043"},{"key":"c4","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.0201"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1177\/014107680009300808"},{"key":"c6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.10034.x"},{"key":"c7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2011.08.047"},{"key":"c8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2008.00712_1.x"},{"key":"c9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.11.040"},{"key":"c10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.08.031"},{"key":"c11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2000.00087.x"},{"key":"c12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.11.017"},{"key":"c13","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.372"},{"key":"c14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1996.tb07942.x"},{"key":"c15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09198.x"},{"key":"c16","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.255"},{"key":"c17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2012.01552.x"},{"key":"c18","first-page":"307","volume":"70","author":"Aithal V","year":"2004","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"c19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.01.018"},{"key":"c20","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.472"},{"key":"c21","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17928"},{"key":"c22","unstructured":"Hurley HJ.                   Axillary hyperhidrosis, apocrine bromhidrosis, hidradenitis                   suppurativa, and familial benign pemphigus: surgical approach. In:                   Roenigk RK,                         Roenigk HH, editors.                      Dermatologic surgery. New York; Dekker:                   1989. 729\u2013739."},{"key":"c23","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13777"},{"key":"c24","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-018-4919-5"},{"key":"c25","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14464"},{"key":"c26","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1014163"},{"key":"c27","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-198703000-00009"},{"key":"c28","doi-asserted-by":"publisher","DOI":"10.1159\/000477459"},{"key":"c29","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12966"},{"key":"c30","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70272-5"},{"key":"c31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.11.035"},{"key":"c32","doi-asserted-by":"publisher","DOI":"10.1159\/000228337"},{"key":"c33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.05.040"},{"key":"c34","doi-asserted-by":"publisher","DOI":"10.1159\/000329023"},{"key":"c35","doi-asserted-by":"publisher","DOI":"10.1159\/000182261"},{"key":"c36","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17151"},{"key":"c37","doi-asserted-by":"publisher","DOI":"10.1159\/000100883"},{"key":"c38","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12857"},{"key":"c39","doi-asserted-by":"publisher","DOI":"10.1159\/000503606"},{"key":"c40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.07.043"},{"key":"c41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.12.018"},{"key":"c42","first-page":"698","volume":"17","author":"Dahmen RA","year":"2019","journal-title":"J Dtsch Dermatol Ges"},{"key":"c43","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16183"},{"key":"c44","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X19847359"},{"key":"c45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.12.004"}],"container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a003693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T15:05:07Z","timestamp":1625065507000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a003693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":45,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1024\/1661-8157\/a003693"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a003693","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}