{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T22:12:04Z","timestamp":1747174324534,"version":"3.40.5"},"reference-count":22,"publisher":"Hogrefe Publishing Group","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:p> Zusammenfassung. Die Abkl\u00e4rung einer Hyperkalz\u00e4mie bedarf einer genauen Anamnese, einer fokussierten klinischen Untersuchung, erg\u00e4nzt durch eine stufenweise durchgef\u00fchrte, prim\u00e4r laborchemische Diagnostik, um zielgerichtet die \u00e4tiologische Zuordnung zu erm\u00f6glichen. Zentral ist hierbei die korrekte Bestimmung der Kalz\u00e4mie und der Korrelation mit der Konzentration von Parathormon (PTH). Der prim\u00e4re Hyperparathyreoidismus oder Malignom-bedingte Hyperkalz\u00e4mien stellen mit rund 90% die mit Abstand h\u00e4ufigsten Ursachen dar und sollten daher stets ber\u00fccksichtigt werden. Die Therapie der Hyperkalz\u00e4mie richtet sich grundlegend nach der \u00c4tiologie sowie nach dem Schweregrad der Elektrolytst\u00f6rung. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003888","type":"journal-article","created":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T07:02:00Z","timestamp":1663138920000},"page":"675-681","source":"Crossref","is-referenced-by-count":1,"title":["Hyperkalz\u00e4mie \u2013 Diagnose, Abkl\u00e4rung und                Therapie"],"prefix":"10.1024","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9883-0608","authenticated-orcid":true,"given":"Markus","family":"Koster","sequence":"first","affiliation":[{"name":"1 Klinik f\u00fcr Allgemeine Innere Medizin\/Hausarztmedizin, Kantonsspital                St. Gallen, St. Gallen, Schweiz"},{"name":"Klinik f\u00fcr Endokrinologie, Diabetologie, Osteologie und                Stoffwechselerkrankungen, Kantonsspital St. Gallen, St. Gallen,                   Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3228-0313","authenticated-orcid":true,"given":"Michael","family":"Br\u00e4ndle","sequence":"additional","affiliation":[{"name":"1 Klinik f\u00fcr Allgemeine Innere Medizin\/Hausarztmedizin, Kantonsspital                St. Gallen, St. Gallen, Schweiz"},{"name":"Klinik f\u00fcr Endokrinologie, Diabetologie, Osteologie und                Stoffwechselerkrankungen, Kantonsspital St. Gallen, St. Gallen,                   Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"doi-asserted-by":"publisher","key":"c1","DOI":"10.1136\/bmj.h2723"},{"doi-asserted-by":"publisher","key":"c2","DOI":"10.1210\/er.2016-1070"},{"doi-asserted-by":"publisher","key":"c3","DOI":"10.1024\/1661-8157.98.5.233"},{"doi-asserted-by":"publisher","key":"c4","DOI":"10.1016\/S0140-6736(17)31430-7"},{"doi-asserted-by":"publisher","key":"c5","DOI":"10.4414\/smf.2017.02931"},{"doi-asserted-by":"publisher","key":"c6","DOI":"10.1200\/JOP.2016.011155"},{"doi-asserted-by":"publisher","key":"c7","DOI":"10.4414\/smf.2016.02776"},{"doi-asserted-by":"publisher","key":"c8","DOI":"10.1016\/j.amjmed.2006.07.044"},{"doi-asserted-by":"publisher","key":"c9","DOI":"10.1210\/jc.2018-01225"},{"doi-asserted-by":"publisher","key":"c10","DOI":"10.1210\/jc.2014-1413"},{"doi-asserted-by":"publisher","key":"c11","DOI":"10.1530\/EJE-21-1044"},{"doi-asserted-by":"publisher","key":"c12","DOI":"10.3322\/caac.21489"},{"doi-asserted-by":"publisher","key":"c13","DOI":"10.1024\/1661-8157\/a003234"},{"doi-asserted-by":"publisher","key":"c14","DOI":"10.1530\/EJE-17-0938"},{"doi-asserted-by":"publisher","key":"c15","DOI":"10.1530\/EJE-18-0051"},{"doi-asserted-by":"publisher","key":"c16","DOI":"10.1210\/clinem\/dgab504"},{"doi-asserted-by":"publisher","key":"c17","DOI":"10.1007\/s00520-012-1683-5"},{"doi-asserted-by":"publisher","key":"c18","DOI":"10.7326\/0003-4819-149-4-200808190-00007"},{"doi-asserted-by":"publisher","key":"c19","DOI":"10.1210\/jc.2014-1001"},{"doi-asserted-by":"publisher","key":"c20","DOI":"10.1136\/bcr-2019-233853"},{"doi-asserted-by":"publisher","key":"c21","DOI":"10.1210\/jcem-56-3-572"},{"doi-asserted-by":"publisher","key":"c22","DOI":"10.1056\/NEJM200012213432508"}],"container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a003888","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T09:41:19Z","timestamp":1677231679000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a003888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1024\/1661-8157\/a003888"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a003888","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"type":"print","value":"1661-8157"},{"type":"electronic","value":"1661-8165"}],"subject":[],"published":{"date-parts":[[2022,9]]}}}