{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,10,27]],"date-time":"2022-10-27T05:00:22Z","timestamp":1666846822563},"reference-count":6,"publisher":"Hogrefe Publishing Group","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:p> Zusammenfassung. Die Borreliose ist die h\u00e4ufigste durch Zecken \u00fcbertragene Infektionskrankheit in Europa. Bakterien aus dem Borrelia-burgdorferi-Komplex werden hier durch Zecken auf den Menschen \u00fcbertragen. Initial kommt es h\u00e4ufig an der Einstichstelle zu einem lokalen Befund (Erythema migrans). Wird dieser Lokalbefund nicht antimikrobiell behandelt, kann es zu einer disseminierten Erkrankung kommen, welche sich als Lyme-Neuroborreliose, als Lyme-Karditis, als Lyme-Arthritis oder als Acrodermatitis chronica atrophicans \u00e4ussert. Eine Neuroborreliose kommt bei 3\u201315% der F\u00e4lle vor. Die mit Abstand h\u00e4ufigste Form der Neuroborreliose ist die Meningoradikuloneuritis der Hirnnerven. Weitere m\u00f6gliche Manifestationen sind die Polyradikulitis, die Meningitis und selten die Enzephalomyelitis. Die Antibiotikabehandlung der Neuroborreliose kann mit Doxycyclin, Ceftriaxon oder Penicillin G erfolgen. Die Prophylaxe der Erkrankung besteht derzeit aus der Expositionsprophylaxe. Eine polyvalente OspA-Impfung ist f\u00fcr Europa zurzeit in Entwicklung. <\/jats:p>","DOI":"10.1024\/1661-8157\/a003939","type":"journal-article","created":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T07:01:45Z","timestamp":1666767705000},"page":"779-787","source":"Crossref","is-referenced-by-count":0,"title":["CME: Neuroborreliose CME-Fragen"],"prefix":"10.1024","volume":"111","author":[{"given":"Laura","family":"Iven-Assmann","sequence":"first","affiliation":[{"name":"Innere Medizin, Kantonsspital Graub\u00fcnden,                Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Szajek","sequence":"additional","affiliation":[{"name":"Innere Medizin, Kantonsspital Graub\u00fcnden,                Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf","family":"Sturzenegger","sequence":"additional","affiliation":[{"name":"Neurologie, Kantonsspital Graub\u00fcnden, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexia","family":"Cusini","sequence":"additional","affiliation":[{"name":"Infektiologie, Kantonsspital Graub\u00fcnden,                Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Fehr","sequence":"additional","affiliation":[{"name":"Innere Medizin, Kantonsspital Graub\u00fcnden,                Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","reference":[{"key":"c1","unstructured":"Rauer S , \n                     Kastenbauer S , et al.\n                  Neuroborreliose, S3-Leitlinie, 2018; in:\n                  Deutsche Gesellschaft f\u00fcr Neurologie (Hrsg.),  Leitlinien f\u00fcr Diagnostik und Therapie in der Neurologie . www.dgn.org\/leitlinien; letzter Zugriff:\n               03.08.2022."},{"key":"c2","unstructured":"Rauer S , \n                     Kastenbauer S , \n                     Hofmann H  , et al.  Guidelines for diagnosis and treatment in neurology \u2013 Lyme\n                  neuroborreliosis.  Ger Med Sci . 2020; 18 :Doc03. DOI:\n                  10.3205\/000279."},{"key":"c3","unstructured":"Linden H  . Clinical manifestations of Lyme disease in adults. MD\n                  UpToDate. 2021. https:\/\/www.uptodate.com\/contents\/\n                  clinical-manifestations-of-lyme-disease-in-adults; letzter\n                  Zugriff: 03.08.2022."},{"key":"#cr-split#-c4.1","doi-asserted-by":"crossref","unstructured":"Nemeth J ,   Bernasconi E ,   Heininger U , et al. Update of the Swiss guidelines on post-treatment Lyme disease  syndrome. Swiss Med Wkly. 2016 Dec 5","DOI":"10.4414\/smw.2016.14353"},{"key":"#cr-split#-c4.2","doi-asserted-by":"crossref","unstructured":"146 :w14353. DOI: 10.4414\/smw.  2016.14353.","DOI":"10.4414\/smw"},{"key":"c5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2020.101411"}],"container-title":["Praxis"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/1661-8157\/a003939","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T07:03:28Z","timestamp":1666767808000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/1661-8157\/a003939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":6,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1024\/1661-8157\/a003939"],"URL":"https:\/\/doi.org\/10.1024\/1661-8157\/a003939","relation":{},"ISSN":["1661-8157","1661-8165"],"issn-type":[{"value":"1661-8157","type":"print"},{"value":"1661-8165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}