{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T08:09:47Z","timestamp":1782806987757,"version":"3.54.5"},"reference-count":36,"publisher":"Hogrefe Publishing Group","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Praxis"],"published-print":{"date-parts":[[2022,12]]},"abstract":" Zusammenfassung. Tiefdermale Defekte k\u00f6nnen durch Verbrennungen, nekrotisierende Fasziitis und schwere Weichteiltraumata entstehen. Die physiologische Narbenrestriktion w\u00e4hrend der Wundheilung wird proportional zur betroffenen Fl\u00e4che immer relevanter. Sie ist f\u00fcr die allgemeine Mobilit\u00e4t der Patientinnen und Patienten massiv einschr\u00e4nkend. Durch \u00e4ussere mechanische Einfl\u00fcsse (Aktivit\u00e4t oder Immobilisation im Alltag) k\u00f6nnen sich ausgepr\u00e4gte Narbenstr\u00e4nge und Adh\u00e4sionen bilden. Eine \u00dcberbelastung endet in einer erneuten Entz\u00fcndungsreaktion und somit in einer weiteren Restriktion. Ad\u00e4quate mechanische Reize k\u00f6nnen das Narbengewebe positiv beeinflussen. Der aktuelle Stand der Forschung l\u00e4sst keinen direkten Transfer in die klinische Behandlung von grossfl\u00e4chigen Narben zu. Die kontinuierliche klinische Umsetzung von Studienresultaten hinsichtlich der Mechanosensitivi\u00e4t isolierter Fibroblasten und stetiges Adaptieren von manuellen Techniken bilden dennoch eine evidenzbasierte Grundlage f\u00fcr die manuelle Narbentherapie. 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