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Psychosomatik in der Gastroenterologie und\n                     Hepatologie [Internet]. Wien;\n                  Springer: 2007. https:\/\/www.springer.com\/de\/book\/9783211691588; letzter\n                  Zugriff: 18.03.2021.","key":"c8","DOI":"10.1007\/978-3-211-69159-5"},{"key":"c9","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1007\/BF01303162","volume":"38","author":"Drossman DA","year":"1993","journal-title":"Dig Dis Sci"},{"key":"c10","doi-asserted-by":"crossref","first-page":"II37","DOI":"10.1136\/gut.45.2008.ii37","volume":"45","author":"Talley NJ","year":"1999","journal-title":"Gut"},{"key":"c11","first-page":"S0016","author":"Mearin F","year":"2016","journal-title":"Gastroenterology"},{"unstructured":"Talley N , et al.  Gastroduodenal disorders. In:  \n                     Drossmann DA , et al.  (eds.). Rome IV: functional\n                     gastrointestinal disorders, 4th ed. 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