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A time\u2010stratified case\u2010crossover study was conducted among 31,810 older adults who were admitted to hospital for sequelae of stroke in Guangzhou, China during 2016\u20132019. For each subject, daily residential exposure to fine particulate matter (PM<jats:sub>2.5<\/jats:sub>), inhalable particulate matter (PM<jats:sub>10<\/jats:sub>), sulfur dioxide (SO<jats:sub>2<\/jats:sub>), nitrogen dioxide (NO<jats:sub>2<\/jats:sub>), carbon monoxide (CO), and ozone (O<jats:sub>3<\/jats:sub>) was extracted from a validated grid data set. Conditional logistic regression models were used for exposure\u2010response analyses. In single\u2010pollutant models, each interquartile range (IQR) increase of lag 04\u2010day exposure to CO (IQR: 0.25\u00a0mg\/m<jats:sup>3<\/jats:sup>) and lag 3\u2010day exposure to O<jats:sub>3<\/jats:sub> (69.6\u00a0\u03bcg\/m<jats:sup>3<\/jats:sup>) was significantly associated with a 4.53% (95% confidence interval: 1.67%, 7.47%) and 5.63% (1.92%, 9.48%) increase in odds of hospital admissions for sequelae of stroke, respectively. These associations did not significantly vary across age or sex. With further adjustment for each of the other pollutants in 2\u2010pollutant models, the association for CO did not change significantly, while the association for O<jats:sub>3<\/jats:sub> disappeared. We estimated that 7.72% of the hospital admissions were attributable to CO exposures. No significant or consistent association was observed for exposure to PM<jats:sub>2.5<\/jats:sub>, PM<jats:sub>10<\/jats:sub>, SO<jats:sub>2<\/jats:sub>, or NO<jats:sub>2<\/jats:sub>. In conclusion, short\u2010term exposure to ambient CO, even at levels below the WHO air quality guideline, was significantly associated with an increased odds of hospital admissions for sequelae of stroke, which may lead to considerable excess hospital admissions.<\/jats:p>","DOI":"10.1029\/2022gh000700","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T06:21:00Z","timestamp":1668752460000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Short\u2010Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults"],"prefix":"10.1029","volume":"6","author":[{"given":"Rui","family":"Wang","sequence":"first","affiliation":[{"name":"Luohu District Chronic Disease Hospital  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruijun","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology School of Public Health Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Atmospheric and Oceanic Science Earth System Science Interdisciplinary Center University of Maryland  College Park MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology School of Public Health Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunshao","family":"Ye","sequence":"additional","affiliation":[{"name":"Guangzhou Health Technology Identification &amp; 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